Taven EZ 10/10 Tablet
Atorvastatin + Ezetimibe
10 mg+10 mg
Renata PLC.
| Pack size | 20's pack |
|---|---|
| Unite Price | 14.00 BDT |
Indications
Taven EZ 10/10 Tablet is used for:
Hypercholesterolaemia, Primary Hyperlipidemia
Adult Dose
Oral
Hypercholesterolaemia
Adult: Per tablet contains atorvastatin 10 mg and ezetimibe 10 mg: Usual starting: 1 tablet once daily.
Child Dose
Safety and efficacy not established
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity; active liver disease or unexplained persistent elevated liver function tests. Pregnancy and lactation.
Precautions
Hepatic impairment; patients consuming substantial quantities of alcohol with a history of liver disease. Not recommended for use in children <10 yr.
Lactation: Because of the potential for adverse reactions in nursing infants, women taking this drug should not breast feed. Contraindicated in breastfeeding women.
Pregnancy-Lactation
Pregnancy Category: X
Lactation: Because of the potential for adverse reactions in nursing infants, women taking this drug should not breast feed. Contraindicated in breastfeeding women.
Interactions
Atorvastatin: Increases digoxin levels; increases anticoagulant effect of warfarin. Avoid the combination of HMG-CoA reductase inhibitors and fibrates. Ezetimibe: Cholestyramine decreases AUC of ezetimibe by approx 55%; ciclosporin may increase ezetimibe levels.
Potentially Fatal: Antacids decrease atorvastatin levels; colestipol decreases atorvastatin plasma levels; propranolol decreases antihyperlipidaemic activity of atorvastatin.
Side Effects
Side effects of Atorvastatin + Ezetimibe :
1-10%
Increased ALT (5%), Increased AST (4%), Musculoskeletal pain (4%), Abdominal pain (3%), Nausea (3%), Arthralgias (3%), Muscle weakness (2%), Dizziness (2%), Hyperkalemia (2%), Hot flushes (2%), Coughing (2%), Bronchitis (2%), Sinusitis (2%)
Mode of Action
Atorvastatin competitively inhibits HMG-CoA reductase, the enzyme that catalyses the conversion of HMG-CoA to mevalonate which is an early rate-limiting step in cholesterol biosynthesis. Ezetimibe inhibits the absorption of cholesterol from the intestine, thus decreasing the delivery of intestinal cholesterol to the liver.
Note
Taven EZ 10/10 10 mg+10 mg Tablet generic name is Atorvastatin + Ezetimibe. Taven EZ 10/10 10 mg+10 mg Tablet is manufactured by Renata PLC.Taven EZ 10/10 is availble in all over Bangladesh.
Mes BD drug index information on Taven EZ 10/10 Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.