Indications
Rhinor MR Tablet is used for:
Allergic conditions
Adult Dose
Oral
Allergic conditions
Adult: 10 mg daily.
Elderly: 10 mg daily.
Child Dose
Oral
Allergic conditions
Child: >12 yr: 10 mg daily.
Renal Dose
Administration
Contra Indications
Significant cardiac or hepatic disease; electrolyte imbalance, particularly hypokalaemia; known or suspected QT prolongation. Clinically significant bradycardia.
Precautions
May impair ability to drive or operate machinery. Elderly. Pregnancy (avoid in 1st trimester) and lactation.
Pregnancy-Lactation
Interactions
Antidepressants and anxiolytics may enhance sedative effect. Potent inhibitors of or substrates for the hepatic metabolism of mizolastine (e.g. cimetidine, ciclosporin, nifedipine) may alter its metabolism.
Potentially Fatal: Increased risk of cardiac arrhythmias with drugs known to prolong the QT interval e.g. class I and III antiarryhthmics. Increased plasma concentrations with macrolide antibiotics and imidazole antifungals.
Side Effects
Side effects of Mizolastine :
Dry mouth, diarrhoea, abdominal pain, nausea; transient drowsiness, headache, dizziness; anxiety and depression; raised liver enzymes: low neutrophil count; transient asthenia, increased appetite associated with wt gain; allergic reactions e.g. angioedema, generalised rash/urticaria, pruritus and hypotension; tachycardia, palpitations; vasovagal attack; arthralgia and myalgia.
Potentially Fatal: Anaphylaxis.
Mode of Action
Mizolastine, a non-sedating antihistamine, blocks histamine H1-receptors on effector cells of the GI tract, blood vessels and respiratory tract. It also has mast-cell stabilising properties.
Note
Rhinor MR 10mg Tablet generic name is Mizolastine. Rhinor MR 10mg Tablet is manufactured by Opsonin Pharma LimitedRhinor MR is availble in all over Bangladesh.
Mes BD drug index information on Rhinor MR Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.