ALERGIX MR Tablet

Mizolastine
10 mg
Incepta Pharmaceuticals Ltd.
Pack size 30's pack
Unite Price 6.50 BDT

Indications

ALERGIX MR Tablet is used for: Allergic conditions

Adult Dose

Oral Allergic conditions Adult: 10 mg daily. Elderly: 10 mg daily.

Child Dose

Oral Allergic conditions Child: >12 yr: 10 mg daily.

Renal Dose

Administration

Contra Indications

Significant cardiac or hepatic disease; electrolyte imbalance, particularly hypokalaemia; known or suspected QT prolongation. Clinically significant bradycardia.

Precautions

May impair ability to drive or operate machinery. Elderly. Pregnancy (avoid in 1st trimester) and lactation.

Pregnancy-Lactation

Interactions

Antidepressants and anxiolytics may enhance sedative effect. Potent inhibitors of or substrates for the hepatic metabolism of mizolastine (e.g. cimetidine, ciclosporin, nifedipine) may alter its metabolism. Potentially Fatal: Increased risk of cardiac arrhythmias with drugs known to prolong the QT interval e.g. class I and III antiarryhthmics. Increased plasma concentrations with macrolide antibiotics and imidazole antifungals.

Side Effects

Side effects of Mizolastine : Dry mouth, diarrhoea, abdominal pain, nausea; transient drowsiness, headache, dizziness; anxiety and depression; raised liver enzymes: low neutrophil count; transient asthenia, increased appetite associated with wt gain; allergic reactions e.g. angioedema, generalised rash/urticaria, pruritus and hypotension; tachycardia, palpitations; vasovagal attack; arthralgia and myalgia. Potentially Fatal: Anaphylaxis.

Mode of Action

Mizolastine, a non-sedating antihistamine, blocks histamine H1-receptors on effector cells of the GI tract, blood vessels and respiratory tract. It also has mast-cell stabilising properties.

Note

ALERGIX MR 10 mg Tablet generic name is Mizolastine. ALERGIX MR 10 mg Tablet is manufactured by Incepta Pharmaceuticals Ltd.ALERGIX MR is availble in all over Bangladesh. Mes BD drug index information on ALERGIX MR Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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