Indications
Lactitab Tablet is used for:
Hypertension, Storke prevention
Adult Dose
Oral
Hypertension
Adult: Initially, 2 mg once daily, may increase after 3-4 wk to 4 mg/day. Max: 6 mg/day.
Hepatic impairment: Severe: Reduce dose.
Child Dose
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Within 1 mth of MI, cardiogenic shock, unstable angina, aortic stenosis.
Precautions
Conduction abnormalities, congenital or acquired QT prolongation, poor cardiac reserve. Hepatic impairment. Pregnancy and lactation.
Pregnancy-Lactation
Interactions
Additive effect w/ diuretics, ACE inhibitors and beta-blockers. May increase plasma level w/ cimetidine. Metabolism may be affected by CYP3A4 inhibitors (e.g. itraconazole) and inducers (e.g. rifampicin). May attenuate antihypertensive effect w/ corticoids or tetracosactid
Side Effects
Side effects of Lacidipine :
Headache, flushing, oedema, dizziness, palpitations, aggravation of angina, increased alkaline phosphatase. Rarely asthenia, rash (e.g. erythema and itching), gastric upset, nausea, gum hyperplasia, polyuria, muscle cramps, mood disturbances.
Mode of Action
Lacidipine is a potent dihydropyridine Ca antagonist mainly selective for Ca channels in the vascular smooth muscle. It dilates peripheral arterioles resulting in reduced peripheral vascular resistance and BP.
Note
Lactitab 4mg Tablet generic name is Lacidipine. Lactitab 4mg Tablet is manufactured by Acme Laboratories Ltd.Lactitab is availble in all over Bangladesh.
Mes BD drug index information on Lactitab Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.