HepaMerz Tablet
L-Ornithine + L-Aspartate
150 mg + 100 mg
Mundipharma (Bangladesh) Pvt. Ltd.
| Pack size | |
|---|---|
| Unite Price | 18.00 BDT |
Indications
HepaMerz Tablet is used for:
Acute Hepatitis (Viral, non-viral, drug induced), Chronic Hepatitis (with or without hyperammonaemia), Cirrhosis of Liver, Fatty Liver with hyperammonaemia, Hepatic Encephalopathy,
As an adjuvant therapy with all hepatotoxic drugs
Adult Dose
Injection (Infusion Concentrate)
The recommended dose is up to 20 g (4 ampoules daily).
In case of loss of consciousness (pre-coma) and clouding of consciousness (coma) up to 8 ampoule within 24 hours,depending on the severity of the condition.
Oral
1-2 sachets is dissolved in a large amount of fluid (e.g. in a glass of water or juice) and is taken orally 3 times a day.
Child Dose
Renal Dose
Administration
Infusion concentrate
1) Infusion concentrate can be added to any of the conventional intravenous fluids (0.9% sodium chloride, 5% dextrose and Ringer's lactate etc.)
2) The normal dilution rate is 1 ampoule per 100ml of I.V. fluid. However, the dose should not exceed 6 ampoules per 500 ml. infusion. The solution mixtures were stable up to 24 hours.
3) Infusion Rate: 5 g/h at maximum.
Oral
Should be taken during or after meal.
Contra Indications
Patients with severe renal insufficiency.
Precautions
Caution needed for pregnant and breastfeeding women.
Pregnancy-Lactation
Interactions
Side Effects
Side effects of L-Ornithine + L-Aspartate :
Increased wt; depressed mood, sleep disorder, nervousness, loss of libido, altered mood; headache, migraine; nausea, abdominal pain or distension, flatulence, vomiting; diarrhea, acne; alopecia; back pain; breast discomfort, ovarian cyst, hot flush, uterine/vaginal bleeding including spotting; asthenic conditions, irritability etc.
Mode of Action
Endogenous Amino Acids, L-Ornithine and L-Aspartate. After administration, it quickly breaks down into L-Ornithine and L-Aspartate. L-Ornithine being a substrate of urea cycle, converts toxic ammonia into non-toxic urea which is eliminated via kidneys, helping the diseased liver to carry out its normal function smoothly (detoxification). The process lowers the elevated level of ammonia in blood (hyperammonaemia) which is a common problem in most of the liver diseases.
L-Aspartate is an essential component of citric acid cycle which liberates energy (ATP), and thus helps in regeneration of damaged liver cells.
Note
HepaMerz 150 mg + 100 mg Tablet generic name is L-Ornithine + L-Aspartate. HepaMerz 150 mg + 100 mg Tablet is manufactured by Mundipharma (Bangladesh) Pvt. Ltd.HepaMerz is availble in all over Bangladesh.
Mes BD drug index information on HepaMerz Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.