Filazine Tablet

Diethylcarbamazine Citrate
100mg
Hudson Pharmaceuticals Ltd.
Pack size 100's pack
Unite Price 1.3 BDT

Indications

Filazine Tablet is used for: Filariasis, Lymphatic filariasis, Pulmonary eosinophilia, Loiasis, Toxocariasis

Adult Dose

W. Bancrofti, B Malayi Day 1: 50 mg PO PC Day 2: 50 mg TID Day 3: 100 mg TID Day 4-14: 6 mg/kg/day divided TID Loa Loa Day 1: 50 mg PO PC Day 2: 50 mg TID Day 3: 100 mg TID Day 4-21: 9 mg/kg/day divided TID M. Streptocerca 6 mg/kg PO qDay x14 days Pulmonary Eosinophilia, Tropical Pulmonary eosinophilia, tropical: 6 mg/kg/day divided TID x14 days Larva Migrans, Visceral 6 mg/kg/day divided TID x7-10 days

Child Dose

W. Bancrofti, B Malayi Day 1: 1 mg/kg PO PC Day 2: 1 mg/kg PO TID Day 3: 1-2 mg/kg PO TID Day 4-14: 6 mg/kg/day divided TID Loa Loa Day 1: 1 mg/kg PO PC Day 2: 1 mg/kg PO TID Day 3: 1-2 mg/kg PO TID Day 4-21: 9 mg/kg/day divided TID Pulmonary Eosinophilia, Tropical Pulmonary eosinophilia, tropical: 6 mg/kg/day divided TID x14 days Larva Migrans, Visceral 6 mg/kg/day divided TID x7-10 days

Renal Dose

Administration

Contra Indications

Pregnancy, hypersensitivity; lactation; infants, elderly or debilitated patients; impaired renal function; cardiac disease.

Precautions

Patients with poor health. Lactation: not known if excreted in breast milk

Pregnancy-Lactation

Pregnancy Category: X Lactation: not known if excreted in breast milk

Interactions

Side Effects

Side effects of Diethylcarbamazine Citrate : Fever, headache, vomiting, dizziness, drowsiness, nausea, chills. Potentially Fatal: Severe hypersensitivity reactions may occur especially in the treatment of onchocerciasis where rare Mazzotti reaction characterised by rash, itching, headache, muscle and joint pains, tachycardia, postural hypotension may start within 2 hr of drug administration. Encephalitis and retinal haemorrhage.

Mode of Action

Diethylcarbamazine is an anthelmintic that is used in the treatment of lymphatic filariasis. It is active against the microfilariae and adult worms of W. bancrofti, B. malayi, B. timori and Loa loa but only against the microfilariae of O. volvulus. It is also used in treatment of toxocariasis. Repeated courses may be necessary.

Note

Filazine 100mg Tablet generic name is Diethylcarbamazine Citrate. Filazine 100mg Tablet is manufactured by Hudson Pharmaceuticals Ltd.Filazine is availble in all over Bangladesh. Mes BD drug index information on Filazine Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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