Cavazide 150/12.5 Tablet
Hydrochlorothiazide + Irbesartan
150mg+12.5mg
Unimed & Unihealth Manufacturers Ltd.
| Pack size | 30's pack |
|---|---|
| Unite Price | 12.00 BDT |
Indications
Cavazide 150/12.5 Tablet is used for:
Diabetic nephropathy, Hypertension
Adult Dose
Hypertension
150 mg/12.5 mg PO qDay intially; if needed, after 1-2 weeks may titrate up to 300 mg/25 mg PO qDay
Child Dose
Renal Dose
Administration
Contra Indications
Hypersensitivity; pregnancy and lactation.
Precautions
Child <6 yr. Unilateral or bilateral renal artery stenosis; vol or Na depletion; aortic or mitral valve stenosis, hypertrophic cardiomyopathy.
Lactation: discontinue drug or do not nurse
Pregnancy-Lactation
Pregnancy Category: C (1st trimester); D (2nd & 3rd trimesters)
Lactation: discontinue drug or do not nurse
Interactions
Other antihypertensives, lithium, K-sparing diuretics, K supplements, salt substitutes containing K. CNS depressants, antidiabetics, cholestyramine & colestipol resins, corticosteroids, ACTH, digitalis glycosides, antiarrhythmics, NSAIDs, tubocurarine, antigout medications, Ca salts. Alcohol; ?-blockers, diazoxide, atropine, beperiden, amantadine, cyclophosphamide, methotrexate.
Side Effects
Side effects of Hydrochlorothiazide + Irbesartan :
>10%
Irbesartan
Hyperkalemia (19%)
1-10%
Chest pain (2%), Tachycardia (1%), Abnormal urination (2%), Musculoskeletal pain (6%), Flu-like syndrome (3%), Edema (3%), Tachycardia (1%), Chest pain (2%), Creatinine increased (1%), Increased BUN (2%)
Irbesartan
Dizziness (10%), URI (9%), Orthostatic hypotension (5%), Fatigue (4%), Diarrhea (3%), Dyspepsia (2%)
Frequency Not Defined
Hydrochlorothiazide
Anorexia, Epigastric distress, Hypotension, Orthostatic hypotension, Photosensitivity, Anaphylaxis, Anemia, Confusion, Erythema multiforme, Stevens-Johnson syndrome, Exfoliative dermatitis including toxic epidermal necrolysis, Dizziness, Hypokalemia and/or hypomagnesemia, Hyperuricemia, Headache
Mode of Action
Hydrochlorothiazide inhibits the reabsorption of Na and chloride in the distal tubules causing increased excretion of Na and water K and hydrogen ions.
Irbesartan is an angiotensin II receptor antagonist. It blocks the vasoconstricting and aldosterone-secreting effects of angiotensin II by binding to AT1 receptors.
Note
Cavazide 150/12.5 150mg+12.5mg Tablet generic name is Hydrochlorothiazide + Irbesartan. Cavazide 150/12.5 150mg+12.5mg Tablet is manufactured by Unimed & Unihealth Manufacturers Ltd.Cavazide 150/12.5 is availble in all over Bangladesh.
Mes BD drug index information on Cavazide 150/12.5 Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.