Arbitan Plus 75 Tablet
Hydrochlorothiazide + Irbesartan
12.5mg + 75mg
Opsonin Pharma Limited
| Pack size | 30's pack |
|---|---|
| Unite Price | 6.00 BDT |
Indications
Arbitan Plus 75 Tablet is used for:
Diabetic nephropathy, Hypertension
Adult Dose
Hypertension
150 mg/12.5 mg PO qDay intially; if needed, after 1-2 weeks may titrate up to 300 mg/25 mg PO qDay
Child Dose
Renal Dose
Administration
Contra Indications
Hypersensitivity; pregnancy and lactation.
Precautions
Child <6 yr. Unilateral or bilateral renal artery stenosis; vol or Na depletion; aortic or mitral valve stenosis, hypertrophic cardiomyopathy.
Lactation: discontinue drug or do not nurse
Pregnancy-Lactation
Pregnancy Category: C (1st trimester); D (2nd & 3rd trimesters)
Lactation: discontinue drug or do not nurse
Interactions
Other antihypertensives, lithium, K-sparing diuretics, K supplements, salt substitutes containing K. CNS depressants, antidiabetics, cholestyramine & colestipol resins, corticosteroids, ACTH, digitalis glycosides, antiarrhythmics, NSAIDs, tubocurarine, antigout medications, Ca salts. Alcohol; ?-blockers, diazoxide, atropine, beperiden, amantadine, cyclophosphamide, methotrexate.
Side Effects
Side effects of Hydrochlorothiazide + Irbesartan :
>10%
Irbesartan
Hyperkalemia (19%)
1-10%
Chest pain (2%), Tachycardia (1%), Abnormal urination (2%), Musculoskeletal pain (6%), Flu-like syndrome (3%), Edema (3%), Tachycardia (1%), Chest pain (2%), Creatinine increased (1%), Increased BUN (2%)
Irbesartan
Dizziness (10%), URI (9%), Orthostatic hypotension (5%), Fatigue (4%), Diarrhea (3%), Dyspepsia (2%)
Frequency Not Defined
Hydrochlorothiazide
Anorexia, Epigastric distress, Hypotension, Orthostatic hypotension, Photosensitivity, Anaphylaxis, Anemia, Confusion, Erythema multiforme, Stevens-Johnson syndrome, Exfoliative dermatitis including toxic epidermal necrolysis, Dizziness, Hypokalemia and/or hypomagnesemia, Hyperuricemia, Headache
Mode of Action
Hydrochlorothiazide inhibits the reabsorption of Na and chloride in the distal tubules causing increased excretion of Na and water K and hydrogen ions.
Irbesartan is an angiotensin II receptor antagonist. It blocks the vasoconstricting and aldosterone-secreting effects of angiotensin II by binding to AT1 receptors.
Note
Arbitan Plus 75 12.5mg + 75mg Tablet generic name is Hydrochlorothiazide + Irbesartan. Arbitan Plus 75 12.5mg + 75mg Tablet is manufactured by Opsonin Pharma LimitedArbitan Plus 75 is availble in all over Bangladesh.
Mes BD drug index information on Arbitan Plus 75 Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.