Carbizol Tablet

Carbimazole
10mg
Square Pharmaceuticals Ltd.
Pack size 60's Pack
Unite Price 5.00 BDT

Indications

Carbizol Tablet is used for: Grave's disease, Hyperthyroidism, Diabetic nephropathy, Preparation for thyroidectomy

Adult Dose

Oral Hyperthyroidism, Adjunct to radio-iodine therapy, Grave's disease, Preparation for thyroidectomy Adult: Initially, 20-60 mg daily as a single or divided dose, reduced gradually once euthyroidism is achieved. Maintenance: 5-15 mg daily for at least 1 yr or 18 mth. Hepatic impairment: Severe: Contraindicated.

Child Dose

Oral Hyperthyroidism; Adjunct to radio-iodine therapy; Preparation for thyroidectomy Child: 3-17 yr Initially, 15 mg daily, adjusted according to response.

Renal Dose

Administration

May be taken with or without food. Take consistently w/ or w/o meals.

Contra Indications

Hyperthyroidism due to nodular goitre.

Precautions

Liver diseases, pregnancy, lactation.

Pregnancy-Lactation

Interactions

Increased serum levels of theophylline or may develop toxicity. May enhance the effect of anticoagulants. Potentially Fatal: Increased sensitivity to warfarin in hyperthyroidism and careful control required as patient is rendered euthyroid.

Side Effects

Side effects of Carbimazole : Mild leucopaenia, sore throat, mouth ulcers, fever, bruising, malaise; rarely cholestatic jaundice; nephrotic syndrome. Nausea, loss of taste, headache, arthralgia, alopoecia. Potentially Fatal: Agranulocytosis, aplastic anaemia, hypoprothrombinaemia, neutropaenia; hypothyroidism and goitre.

Mode of Action

Carbimazole is metabolised to methimazole which is responsible for its antithyroid action. It blocks the production of thyroid hormones by inhibiting thyroid peroxidase.

Note

Carbizol 10mg Tablet generic name is Carbimazole. Carbizol 10mg Tablet is manufactured by Square Pharmaceuticals Ltd.Carbizol is availble in all over Bangladesh. Mes BD drug index information on Carbizol Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Carbimazole :