Permethrin 5% Topical

Indications

Permethrin 5% Topical is used for: Scabies, Pediculosis pubis

Adult Dose

Topical Scabies Adult: (30 gm tube) : A full tube. Apply to skin surfaces from neck to toes. Wash off after 8-14 hr. May reapply in 7 days Pediculosis capitis, Pediculosis pubis Apply to washed hair and leave on for 10 mins before rinsing with water. May reapply in 7 days

Child Dose

Topical Scabies Children over 12 years(30 gm tube) : A full tube. Children aged 6-12 years : Up to 1/2 of a tube. Children aged 1-5 years : Up to 1/4 of a tube. Children aged 2 months to 1 year: Up to 1/8 of a tube. Apply to skin surfaces from neck to toes. Wash off after 8-14 hr. May reapply in 7 days Pediculosis capitis, Pediculosis pubis Apply to washed hair and leave on for 10 mins before rinsing with water. May reapply in 7 days

Renal Dose

Administration

Contra Indications

Hypersensitivity.

Precautions

Avoid contact with eyes and mucous membranes. Cross-sensitivity may occur with ragweed or chrysanthemums. History of asthma. Pregnancy and lactation. Lactation: Not known if distributed in breast milk; may temporarily withhold the drug while the mother is nursing

Pregnancy-Lactation

Pregnancy Category: B Lactation: Not known if distributed in breast milk; may temporarily withhold the drug while the mother is nursing

Interactions

Mild and transient burning, stinging, pruritus, erythema, tingling, numbness, rash; difficulty in breathing; phototoxic or photosensitisation reactions.

Side Effects

Side effects of Permethrin 5% Topical : 1-10% Mild and transient burning and stinging (10%) Pruritus (7%)

Mode of Action

Permethrin is a pyrethroid pediculocide and scabicide. It causes paralysis and death of the pest by inhibiting sodium ion influx through nerve cell membrane channels delaying repolarisation.