Oxyphenonium Bromide 1% Eye prep

Indications

Oxyphenonium Bromide 1% Eye prep is used for: Dilatation of pupil

Adult Dose

Ophthalmic 1-2 drops or as required.

Child Dose

Renal Dose

Administration

Contra Indications

Patients with urinary obstruction, paralytic ileus and myasthenia gravis.

Precautions

Caution should be exercised in patients with history of high blood pressure, increased eye pressure, elderly, children, during pregnancy and breastfeeding.

Pregnancy-Lactation

Interactions

Side Effects

Side effects of Oxyphenonium Bromide 1% Eye prep : Eye- Blurred vision and sensitivity to sunlight.

Mode of Action

Oxyphenonium is an anticholinergic drug. It exerts its action by inhibiting muscarinic (cholinergic) receptors on smooth muscles, cardiac muscles and prevents the effect of Acetylcholine. Inhibition of Acetylcholine produces relaxation of smooth muscles and prevents the muscle spasm in irritable bowel syndrome. Oxyphenonium also has a direct relaxant effect on smooth muscle. It also inhibits gastrointestinal propulsive movement and decreases gastric acid secretion and control bronchial, pharyngeal and tracheal secretions. It also possesses nicotinic blocking activity and interferes with ganglionic or neuromuscular transmission. It cross the BBB poorly and does not produce CNS effect.