Magaldrate + Simethicone Chewable
Indications
Magaldrate + Simethicone Chewable is used for:
Heartburn, Indigestion, Dyspepsia, Gastritis, Peptic ulcers, GERD
Adult Dose
Oral
Adult
Tablet: 1-3 tablet, after meals and at bed time.
Child Dose
Oral
Children 12 years and older:
Tablet: 1-3 tablet, after meals and at bed time.
Renal Dose
Administration
Take between meals & at bedtime.
Contra Indications
Patients with known hypersensitivity to magnesium and aluminium. It is also contraindicated in patients with impaired renal functions.
Precautions
Care should be taken in decreased kidney function, hypophosphataemia and weak people.
Pregnancy-Lactation
Interactions
Magaldrate may negatively influence drugs like tetracyclines, benzodiazepines, and indomethacin. High doses or prolonged usage may lead to an increment of defecation and a reduction in feces consistence. In some cases it can alter the functionality of the gastrointestinal tract, occasionally provoking constipation or diarrhea.
Side Effects
Side effects of Magaldrate + Simethicone Chewable :
Aluminum oxide
Chalky taste, Constipation, Fecal impaction, Stomach cramps
Frequency Not Defined
Aluminum oxide
Nausea, Vomiting, Aluminum intoxication, Hypophosphatemia, Osteomalacia,
Magnesium oxide
Diarrhea, Hypermagnesemia
Mode of Action
Magaldrate is a hydroxymagnesium aluminate complex that is rapidly converted in gastric acid to magnesium and aluminium hydroxide, which is poorly absorbed and provides a sustained antacid effect with balanced efects on intestinal motility; increases lower esophageal sphincter tone and inhibits smooth muscle contraction and gastric emptying.
Simethicone allows gas bubbles in the stomach and intestines to come together more easily, which allows for easier passage of gas.