Glycopyrronium bromide (Glycopyrrolate) Inhalation

Indications

Glycopyrronium bromide (Glycopyrrolate) Inhalation is used for: Maintenance bronchodilator treatment to relieve symptoms in adult patients with, chronic obstructive pulmonary disease (COPD).

Adult Dose

Inhalation The recommended dosage of Glycopyrronium inhalation: One capsule once daily with the ConviHaler device at the same time of day.

Child Dose

Renal Dose

Administration

Contra Indications

Hypersensitivity to the active substance or to any of the excipients.

Precautions

Glycopyrronium should not be used for the initial treatment of acute episodes of bronchospasm, i.e. rescue therapy. Immediate hypersensitivity reactions may occur after administration of Glycopyrronium inhalation powder. As with other anticholinergic drugs, Glycopyrronium should be used with caution in patients with narrow-angle glaucoma, prostatic hyperplasia or bladder-neck obstruction.

Pregnancy-Lactation

Pregnancy There are no adequate and well-controlled studies in humans Animal studies have not shown teratogenicity Lactation Unknown if distributed in human breast milk Consider the developmental and health benefits of breastfeeding along with the mother’s clinical need for the drug, and any potential adverse effects on the breastfed infant from the drug or from the underlying maternal condition

Interactions

Side Effects

Side effects of Glycopyrronium bromide (Glycopyrrolate) Inhalation : Inhaled medicines may cause inhalation-induced bronchospasm, dehydration, dry mouth, constipation, dizziness, insomnia, skin and subcutaneous tissue disorders, immune system disorders.

Mode of Action

Glycopyrronium is a long-acting, specific antimuscarinic agent, in clinical medicine often called an anticholinergic. It has a similar affinity to the subtypes of muscarinic receptors M1 to M5. In the airways, inhibition of M3-receptors at the smooth muscle results in relaxation.