Gallamine Triethiodide

Indications

Gallamine Triethiodide is used for: Aid controlled ventilation, Muscle relaxant

Adult Dose

Intravenous Muscle relaxant in general anaesthesia; Aid controlled ventilation Adult: Test dose: 20 mg may be given before anesth to determine drug sensitivity. Initially, 80-120 mg via IV inj, further doses of 20-40 mg may be given as required.

Child Dose

Intravenous Muscle relaxant in general anaesthesia; Aid controlled ventilation Child: 1.5 mg/kg. Neonates: 600 mcg/kg.

Renal Dose

Administration

Contra Indications

Severe renal impairment. Hypersensitivity to iodine. Mysasthenia gravis.

Precautions

Careful dose titration and monitoring of the degree of block are required to prevent overdosage.

Pregnancy-Lactation

Interactions

Lidocaine, procainamide, quinidine, and verapamil may enhance the block. Clindamycin can prolong the action of muscle relaxants. Apnoea may be prolonged when used with polymyxins. Anticholinesterases or long-term treatment with corticosteroids may antagonise the action of gallamine.

Side Effects

Side effects of Gallamine Triethiodide : Tachycardia, increased BP.

Mode of Action

Gallamine triethiodide is a benzylisoquinolinium competitive neuromuscular blocker. It is used to produce muscle relaxation in general anaesthesia during surgical procedures and to aid controlled ventilation.