Gallamine Triethiodide
Indications
Gallamine Triethiodide is used for:
Aid controlled ventilation, Muscle relaxant
Adult Dose
Intravenous
Muscle relaxant in general anaesthesia; Aid controlled ventilation
Adult: Test dose: 20 mg may be given before anesth to determine drug sensitivity. Initially, 80-120 mg via IV inj, further doses of 20-40 mg may be given as required.
Child Dose
Intravenous
Muscle relaxant in general anaesthesia; Aid controlled ventilation
Child: 1.5 mg/kg.
Neonates: 600 mcg/kg.
Renal Dose
Administration
Contra Indications
Severe renal impairment. Hypersensitivity to iodine. Mysasthenia gravis.
Precautions
Careful dose titration and monitoring of the degree of block are required to prevent overdosage.
Pregnancy-Lactation
Interactions
Lidocaine, procainamide, quinidine, and verapamil may enhance the block. Clindamycin can prolong the action of muscle relaxants. Apnoea may be prolonged when used with polymyxins. Anticholinesterases or long-term treatment with corticosteroids may antagonise the action of gallamine.
Side Effects
Side effects of Gallamine Triethiodide :
Tachycardia, increased BP.
Mode of Action
Gallamine triethiodide is a benzylisoquinolinium competitive neuromuscular blocker. It is used to produce muscle relaxation in general anaesthesia during surgical procedures and to aid controlled ventilation.