Eflornithine Hydrochloride Monohydrate

Indications

Eflornithine Hydrochloride Monohydrate is used for: Reduction of Facial Hair in Women

Adult Dose

Topical Reduction of Facial Hair in Women Apply to affected area twice daily at least 8 hours apart

Child Dose

Topical Reduction of Facial Hair in Women >12 years: Apply to affected area twice daily at least 8 hours apart

Renal Dose

Administration

Contra Indications

Hypersensitivity

Precautions

Discontinue if sensitivity occurs Lactation: Not known whether distributed into breast milk; use caution

Pregnancy-Lactation

Interactions

Side Effects

Side effects of Eflornithine Hydrochloride Monohydrate : Acne, Pseudofolliculitis barbae, Burning, Stinging, Dry, and/or tingling skin, Erythema, Anorexia, Neutropenia, Rash, Pruritus, Alopecia

Mode of Action

May inhibit ornithine decarboxylase (ODC), an enzyme that catalyzes biosynthesis of intracellular polyamines required for cell division & differentiation, which in turn can affect hair growth