Calcium Dobesilate 4% + Lidocaine 2% + Dexamethasone Acetate 0.025% rectal prep
Indications
Calcium Dobesilate 4% + Lidocaine 2% + Dexamethasone Acetate 0.025% rectal prep is used for:
Internal and external hemorrhoids, anal pruritus, anal eczema, anitis, perianitis, acute hemorrhoidal thrombosis and anal fissure. Pre and postoperative treatment in cases of hemorrhoidectomy
Adult Dose
Rectal Ointment
Apply 2 -3 times daily.
Apply in the morning and bedtime and if possible after defecation. In case of external hemorrhoids or anal pruritus, apply a thin layer of the ointment several times a day.
The duration of the treatment is generally of few days.
Child Dose
Renal Dose
In case of renal insufficiency, this oinement should not be used during longer periods. Avoid long-lasting treatments.
Administration
Apply in the morning and bedtime and if possible after defecation. If the ointment is preferred, use the applicator by screwing it to the tube. Insert the applicator as deep as possible in the anus then press the tube gently while withdrawing it.
Contra Indications
Hypersensitivity
Precautions
In case of renal insufficiency, this ointment should not be used during longer periods. Avoid long-lasting treatments.
Lactation: Calcium Dobesilate is excreted in the maternal milk in low amounts but it is not known whether this is the case with local use. After topical administration, Lidocaine Hydrochloride and Dexamethasone Acetate are excreted in the maternal milk. As a precaution, it should be decided between discontinuing the treatment or the breast-feeding.
Pregnancy-Lactation
Interactions
Side Effects
Side effects of Calcium Dobesilate 4% + Lidocaine 2% + Dexamethasone Acetate 0.025% rectal prep :
Very rare cases have been reported: Modifications of the intestinal transit, temporary burning sensation and local pain. Hypersensitivity reactions together with skin reactions and/or fever can occur. These reactions can be of allergic origin and in this case, the treatment must be discontinued.
Mode of Action
Calcium Dobesilate acts on the capillary walls by regulating their impaired physiological functions - i.e. increased permeability and decreased resistance and on different signs of inflammation. It also has an antithrombotic activity.
Lidocaine hydrochloride, a local anesthetic, contributes to relieve pain.
Dexamethasone Acetate, a Corticosteroid for topical use, possesses anti-inflammatory and antipruritic actions.