Beclomethasone + Neomycin + Miconazole Topical
Indications
Beclomethasone + Neomycin + Miconazole Topical is used for:
Dermatoses where secondary bacterial and candidal infection present.
Adult Dose
Topical/Cutaneous
Corticosteroid-responsive dermatoses
Adult: Apply cream/ointment onto affected area bid or tid.
Child Dose
Safety and efficacy not established
Renal Dose
Administration
Contra Indications
Hypersensitivity.
Precautions
For external use only.
Children, elderly; pregnancy and lactation.
Pregnancy-Lactation
Interactions
Side Effects
Side effects of Beclomethasone + Neomycin + Miconazole Topical :
Loss of skin collagen and SC atrophy; local hypopigmentation of deeply pigmented skin; local irritation, burning, contact dermatitis
Mode of Action
Beclometasone controls the rate of protein synthesis, depresses the migration of polymorphonuclear leukocytes, fibroblasts, reverses capillary permeability and lysosomal stabilisation at the cellular level to prevent or control inflammation.
Miconazole inhibits ergosterol synthesis thus damaging fungal cell wall membrane and increases its permeability, allowing leakage of nutrients.
Neomycin interferes w/ bacterial protein synthesis by binding to 30S ribosomal subunits.