Beclomethasone Dipropionate Nasal prep

Indications

Beclomethasone Dipropionate Nasal prep is used for: Sinusitis, Hay fever, Allergic and non-allergic rhinitis, Nasal Polyps (Postsurgical Prophylaxis), Vasomotor Rhinitis

Adult Dose

Adults: The usual dosage is 1-2 inhalations in each nostril twice a day .

Child Dose

Children 12 Years of Age and Older: The usual dosage is 1-2 inhalations in each nostril twice a day . Children 6 to 12 Years of Age: Patients should be started with 1 inhalation in each nostril twice a day; patients with more severe symptoms may use 2 inhalations in each nostril. <6 years: Safety and efficacy not established

Renal Dose

Administration

Shake well before each use Before first use, prime pump by 6 actuations into air If not used for 7 days, reprime pump until fine spray appears

Contra Indications

patients with a history of hyper-sensitivity to any of the components

Precautions

Nasal passage infections and paranasal sinuses should be appropriately treated. Caution should be exercised whilst transferring patients from systemic steroid treatment to Beclometasone Dipropionate Aqueous Nasal Spray if there is doubt that their adrenal function is impaired. Systemic effects of nasal corticosteroids may occur particularly at high doses prescribed for prolonged periods. Growth retardation has been reported in children receiving nasal corticosteroids at licensed doses. Treatment with higher than recommended doses may result in clinically significant adrenal suppression. If there is evidence for higher than recommended doses being used then additional systemic corticosteroid cover should be considered during periods of stress or elective surgery. Lactation: Unknown whether distributed in breast milk; use caution

Pregnancy-Lactation

Pregnancy Category: C Lactation: Unknown whether distributed in breast milk; use caution

Interactions

Side Effects

Side effects of Beclomethasone Dipropionate Nasal prep : >10% Nasopharyngeal irritation (24%) 1-10% Headache (<5%), Nausea (<5%), Lightheadedness (<5%), Sneezing attacks after administration (4%), Nasal congestion (<3%), Nose bleeds (<3%), Rhinorrhea (<3%), Increased lacrimation (<3%), Epistaxis (<3%) Frequency Not Defined Nasal mucosa ulceration, Nasal septum perforation

Mode of Action

Beclometasone controls the rate of protein synthesis, depresses the migration of polymorphonuclear leukocytes, fibroblasts, reverses capillary permeability and lysosomal stabilisation at the cellular level to prevent or control inflammation.