Zox Powder for Suspension

Nitazoxanide
100mg/5ml
Square Pharmaceuticals Ltd.
Pack size 30m bot
Unite Price 35.00 BDT

Indications

Zox Powder for Suspension is used for: Giardiasis, Cryptosporidiosis

Adult Dose

Oral Giardiasis; Cryptosporidiosis Adult: 500 mg every 12 hr for 3 days.

Child Dose

Oral Giardiasis; Cryptosporidiosis Child: 1-3 yr: 100 mg(5 ml) every 12 hr; 4-11 yr: 200 mg(10ml) every 12 hr; >12 yr: 500 mg every 12 hr. All doses to be taken for 3 days.

Renal Dose

Administration

Should be taken with food.

Contra Indications

Hypersensitivity.

Precautions

Renal and hepatic impairment. Pregnancy and lactation. Children <1 yr.

Pregnancy-Lactation

Interactions

May possibly interact with highly protein-bound drugs e.g. warfarin.

Side Effects

Side effects of Nitazoxanide : 1-10% Headache (1%), Abdominal pain (8%), Diarrhea (2%), Nausea (3%), Chromaturia (2%), Vomiting (1%) <1% Increased ALT, Anorexia, Appetite increased, Creatinine increased, Diaphoresis, Dizziness, Eye discoloration (pale yellow), Fever, Flatulence, Infection, Malaise, Pruritus, Thinitis, Salivary glands enlarged, Urine discoloration

Mode of Action

Nitazoxanide is an antiprotozoal agent. Both nitazoxanide and its active metabolite (tizoxanide) interfere with the pyruvate:ferredoxin 2-oxidoreductase (PFOR) enzyme-dependent electron transfer reaction which is essential to anaerobic metabolism in susceptible organisms.

Note

Zox 100mg/5ml Powder for Suspension generic name is Nitazoxanide. Zox 100mg/5ml Powder for Suspension is manufactured by Square Pharmaceuticals Ltd.Zox is availble in all over Bangladesh. Mes BD drug index information on Zox Powder for Suspension is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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