Indications
Zilcef Tablet is used for:
Pharyngitis, Susceptible infections, Sinusitis, Otitis media, Skin and skin structure infections, Tonsillitis, Respiratory tract infections, Acute Maxillary Sinusitis, Acute bacterial exacerbation of chronic bronchitis
Adult Dose
Pharyngitis & Tonsillitis
500 mg PO qDay for 10 days
Respiratory Tract Infections, Skin Infections
250-500 mg q12hr OR 500 mg qDay for10 days
Child Dose
Child: PO 15–30 mg/kg/day q12h
Renal Dose
Renal impairment:
CrCl (ml/min)
<30 Half normal dose.
Administration
May be taken with or without food. May be taken w/ meals to reduce GI discomfort.
Contra Indications
Hypersensitivity.
Precautions
Hypersensitivity to penicillins; renal impairment; porphyria. Monitor renal and haematologic status. Pregnancy, lactation.
Lactation: low distribution into breast milk; use with caution
Pregnancy-Lactation
Pregnancy Category: B
Lactation: low distribution into breast milk; use with caution
Interactions
Renal excretion delayed by probenecid. Decreases contraceptive effect of oestrogen-containing oral contraceptives.
Side Effects
Side effects of Cefprozil :
1-10%
Nausea (3.5%), Diarrhea (2.9%), Elevated LFTs (2%), Diaper rash (1.5%), Abdominal pain (1%), Dizziness (1%), Vomiting (1%)
<1%
Eosinophilia, Superinfection, Vaginitis, Cholestatic jaundice, Elevated BUN & creatinine, Prolonged PT
Potentially Fatal: Pseudomembranous colitis.
Mode of Action
Cefprozil inhibits cell wall synthesis and has activity against a broad range of gram-positive and gram-negative bacteria.
Note
Zilcef 250mg Tablet generic name is Cefprozil. Zilcef 250mg Tablet is manufactured by Apex Pharma Limited.Zilcef is availble in all over Bangladesh.
Mes BD drug index information on Zilcef Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.