Xalatan Eye Drops

Latanoprostene bunod eye prep
0.01%
Janata Pharma
Pack size 2.5 ml
Unite Price 703.75 BDT

Indications

Xalatan Eye Drops is used for: Elevated Intraocular Pressure

Adult Dose

Elevated Intraocular Pressure Indicated for reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension Instill 1 drop in affected eye(s) qDay in the evening

Child Dose

Elevated Intraocular Pressure Indicated for reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension <16 years: Not recommended due to potential safety concerns related to increased pigmentation following long-term chronic use >16 years: Instill 1 drop in affected eye(s) qDay in the evening

Renal Dose

Administration

Contra Indications

Precautions

Increased pigmentation to tissues may occur; most frequently reported changes with prostaglandin analogs have been of the iris and periorbital tissue (eyelid) and is expected to increase for the duration of treatment; regularly examine patients who develop noticeably increased iris pigmentation Gradual increases in length, thickness, and number of lashes have been reported Caution with a history of intraocular inflammation (iritis/uveitis); avoid if active intraocular inflammation exists, as it may exacerbate this condition Macular edema, including cystoid macular edema, reported; caution in patients with aphakia pseudophakia with a torn posterior lens capsule, or with known risk factors for macular edema Bacterial keratitis associated with the use of multiple-dose containers of topical ophthalmic products has been reported; containers may be inadvertently contaminated by patients who typically had a concurrent corneal disease or an ocular epithelial surface disruption Remove contact lenses before administration because product contains benzalkonium chloride; lenses may be reinserted 15 minutes after administration

Pregnancy-Lactation

Pregnancy There are no available human data for the use during pregnancy to inform any drug associated risks Latanoprostene bunod has caused miscarriages, abortion, and fetal harm in rabbits; when administered IV to pregnant rabbits at exposures ?0.28 times the clinical dose was shown to be abortifacient and teratogenic Doses >20 mcg/kg/day (23 times the clinical dose) produced 100% embryofetal lethality; structural abnormalities (eg, anomalies of the great vessels and aortic arch vessels, domed head, sternebral and vertebral skeletal anomalies, limb hyperextension and malrotation, abdominal distension and edema) were observed in rabbit fetuses Latanoprostene bunod was not teratogenic rats when administered IV at 150 mcg/kg/day (87 times the clinical dose) Lactation There are no data on the presence of latanoprostene bunod in human milk, the effects on the breastfed infant, or the effects on milk production Developmental and health benefits of breastfeeding should be considered, along with the mother’s clinical need for latanoprostene bunod, and any potential adverse effects on the breastfed infant from latanoprostene bunod

Interactions

Side Effects

Side effects of Latanoprostene bunod eye prep : 1-10% Hyperemia (6%) Eye irritation (4%) Eye pain (3%) Instillation site pain (2%)

Mode of Action

Believed to lower intraocular pressure by increasing outflow of aqueous humor through the trabecular meshwork and uveoscleral routes Intraocular pressure is a major risk factor for glaucoma progression; reduction of intraocular pressure reduces risk of glaucomatous visual field loss

Note

Xalatan 0.01% Eye Drops generic name is Latanoprostene bunod eye prep. Xalatan 0.01% Eye Drops is manufactured by Janata PharmaXalatan is availble in all over Bangladesh. Mes BD drug index information on Xalatan Eye Drops is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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