Vilaptin Tablet

Vildagliptin
50 mg
United Chemicals & Pharmaceuticals Ltd.
Pack size 30's pack
Unite Price 20.08 BDT

Indications

Vilaptin Tablet is used for: Type 2 DM

Adult Dose

Oral Type 2 diabetes mellitus Adult: 50 mg bid. Not recommended to use >100 mg/day. W/ metformin or a thiazolidinedione: 50 mg twice daily; w/ a sulfonylurea: 50 mg/day in the morning.

Child Dose

Renal Dose

Renal impairment: Moderate, severe and ESRD: 50 mg once daily.

Administration

May be taken with or without food.

Contra Indications

Hypersensitivity to vildagliptin

Precautions

Patient w/ cardiac failure (NYHA functional class IV), type 1 DM; history of acute pancreatitis. Not intended for the treatment of diabetic ketoacidosis. Hepatic impairment, including patients w/ pre-treatment ALT or AST >3 times the upper limit of normal (ULN). Moderate or severe renal impairment, ESRD. Monitoring Parameters Monitor liver function.

Pregnancy-Lactation

Interactions

Decreased hypoglycaemic effect w/ thiazides, corticosteroids, thyroid products and sympathomimetics.

Side Effects

Side effects of Vildagliptin : Nausea, peripheral oedema, headache, tremor, asthenia, dizziness, constipation, hypoglycaemia, arthralgia, hepatic dysfunction, nasopharyngitis, upper resp tract infection, pancreatitis, exfoliative and bullous skin reactions.

Mode of Action

Vildagliptin is a dipeptidylpeptidase-4 (DPP-4) inhibitor that improves glycaemic control by preventing DPP-4 from inactivating the incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide, thus prolonging incretin activity in response to ingestion of nutrients. This increases insulin sensitivity, decreases glucagon secretion and improves ?-cell function.

Note

Vilaptin 50 mg Tablet generic name is Vildagliptin. Vilaptin 50 mg Tablet is manufactured by United Chemicals & Pharmaceuticals Ltd.Vilaptin is availble in all over Bangladesh. Mes BD drug index information on Vilaptin Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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