Urtizin Tablet
Hydroxyzine Hydrochloride
10 mg
Unimed & Unihealth Manufacturers Ltd.
| Pack size | |
|---|---|
| Unite Price | 1.25 BDT |
Indications
Urtizin Tablet is used for:
Pruritus, Allergic conditions, Generalized anxiety disorder, Psychoneurosis, Chronic urticaria, Atopic or contact dermatoses, Pre- or post-operative sedation
Adult Dose
Oral
For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested:
Adult: 50-100 mg 4 times daily.
For use in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus:
Adult: Initially, 25 mg at night increased if required up to 25 mg 3-4 times daily.
As a sedative when used as a premedication and following general anesthesia:
Adult: 50-100 mg.
Hepatic impairment: Reduce total daily dose by 33%.
Child Dose
Oral
For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested
Children under 6 years: 50 mg daily in divided doses
>6 years: 50 to 100 mg daily in divided doses.
For use in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus
Child: 6 mth to 6 yr Initially, 5-15 mg/day, increased to 50 mg/day in divided doses;
>6 yr Initially, 15-25 mg/day, increased up to 50-100 mg/day in divided doses.
As a sedative when used as a premedication and following general anesthesia
Child: 0.6 mg/kg.
Hepatic impairment: Reduce total daily dose by 33%.
For symptomatic relief of anxiety and tension associated with psychoneurosis and as an adjunct in organic disease states in which anxiety is manifested,children under 6 years, 50 mg daily in divided doses and over 6 years, 50 to 100 mg daily in divided doses.
For use in the management of pruritus due to allergic conditions such as chronic urticaria and atopic and contact dermatoses, and in histamine-mediated pruritus, children under 6 years, 50 mg daily in divided doses and over 6 years, 50 to 100 mg daily in divided doses.
As a sedative when used as a premedication and following general anesthesia, 0.6 mg/kg in children.
Renal Dose
Renal Impairment
>50 mL/min: Dose adjustment not necessary
<50 mL/min: Administer 50% normal dose
Administration
May be taken with or without food.
Contra Indications
Porphyria, neonates, pregnancy, lactation.
Precautions
Renal and hepatic impairment; narrow-angle glaucoma; epilepsy; prostatic hypertrophy; bladder neck obstruction; asthma; COPD. May impair ability to drive or operate machinery.
Lactation: Excretion in milk unknown; use with caution
Pregnancy-Lactation
Pregnancy category: Considered to be contraindicated in early (1st trimester) pregnancy until more human pregnancy data available; limited experience in human pregnancy, either for drug itself or drugs in same class or with similar mechanisms of action, including 1st trimester, current limited data suggests that the drug does not represent a significant risk of developmental toxicity including growth restriction, structural anomalies, functional/behavioral deficits, or death at any time in pregnancy
Lactation: Excretion in milk unknown; use with caution
Interactions
Additive or may potentiate CNS depressant effects of opiates or other analgesics, barbiturates or other sedatives, and anaesth. MAOIs and TCAs potentiate antimuscarinic effects.
Side Effects
Side effects of Hydroxyzine Hydrochloride :
Dizziness, ataxia, fatigue, drowsiness, hallucination, seizure, dry mouth, nervousness, xerostomia, involuntary movements, slurred speech, headache, paraesthesia, tremor, blurred vision, resp depression, pruritus, rash, urticaria, allergic reaction.
Mode of Action
Hydroxyzine, a piperazine derivative, blocks histamine H1-receptors on effector cells of the GI tract, blood vessels and resp tract. It is a sedating antihistamine w/ antimuscarinic and significant sedative properties. It also possesses skeletal muscle relaxing, bronchodilator, antiemetic and analgesic properties.
Note
Urtizin 10 mg Tablet generic name is Hydroxyzine Hydrochloride. Urtizin 10 mg Tablet is manufactured by Unimed & Unihealth Manufacturers Ltd.Urtizin is availble in all over Bangladesh.
Mes BD drug index information on Urtizin Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.