Tufnil Tablet

Tolfenamic Acid
200mg
Eskayef Pharmaceuticals Ltd.
Pack size 40's Pack
Unite Price 10.00 BDT

Indications

Tufnil Tablet is used for: Mild to moderate pain, Acute migraine attacks

Adult Dose

Oral Acute migraine attacks Adult: 200 mg when 1st symptoms appear, may be repeated after 1-2 hr, if necessary. Mild to moderate pain Adult: 100-200 mg tid. Hepatic impairment: Severe: Avoid.

Child Dose

Renal Dose

Renal impairment: Severe: Avoid.

Administration

Should be taken with food. Take w/ or immediately after meals.

Contra Indications

Hypersensitivity to aspirin or other NSAID. Active or history of GI bleeding or ulceration, severe heart failure, history of GI bleeding or perforation related to previous NSAID therapy. Severe renal and hepatic impairment. Pregnancy (3rd trimester).

Precautions

Patient w/ or w/ history of bronchial asthma, uncontrolled HTN, CHF, established ischaemic heart disease, peripheral arterial disease, cerebrovascular disease, coagulation defects, SLE, connective tissue disorders, history of GI disease (e.g. Crohn's disease, ulcerative colitis). Hepatic and renal impairment. Pregnancy and lactation. Patient Counselling This drug may cause dizziness, drowsiness, fatigue and visual disturbances, if affected, do not drive or operate machinery. Monitoring Parameters Monitor renal function.

Pregnancy-Lactation

Interactions

Increased rate of absorption of tolfenamic acid with metoclopramide and magnesium hydroxide. Decreased rate of absorption of tolfenamic acid with aluminium hydroxide. Increased risk of bleeding with anticoagulants and other NSAIDs. Decreased antihypertensive response to loop diuretics, ?-blockers and ACE inhibitors. Coadmin increased plasma concentrations of lithium, methotrexate and cardiac glycosides. Increased risk of nephrotoxicity with ACE inhibitors, ciclosporin, tacrolimus or diuretics.

Side Effects

Side effects of Tolfenamic Acid : Dysuria esp in males; tremor, euphoria, fatigue, pulmonary infiltration, nausea, vomiting, diarrhoea, flatulence, constipation, dyspepsia, abdominal pain, melaena, haematemesis, ulcerative stomatitis, exacerbation of Crohn's disease and colitis, gastritis, pancreatitis; oedema, HTN, cardiac failure; nephritis, hepatitis, jaundice, abnormal liver function; visual disturbances, optic neuritis, headache, paraesthesia, depression, confusion, hallucinations, tinnitus, vertigo, tremor, dizziness, malaise, drowsiness; thrombocytopenia, neutropenia, agranulocytosis, anaemia. Potentially Fatal: Exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis; GI bleeding, ulceration or perforation.

Mode of Action

Tolfenamic acid, an anthranilic acid derivative, is an NSAID. It has anti-inflammatory, analgesic and antipyretic effects.

Note

Tufnil 200mg Tablet generic name is Tolfenamic Acid. Tufnil 200mg Tablet is manufactured by Eskayef Pharmaceuticals Ltd.Tufnil is availble in all over Bangladesh. Mes BD drug index information on Tufnil Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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