Topicacin Cream
Capsaicin 0.025% topical
25 mg/100 gm
Incepta Pharmaceuticals Ltd.
| Pack size | 20gm tube |
|---|---|
| Unite Price | 50.00 BDT |
Indications
Topicacin Cream is used for:
Rheumatoid arthritis, Osteoarthritis, Psoriasis, Post-herpetic neuralgia, Anogenital pruritus, Sprains, Stiff neck, Low back pain, Trigeminal neuralgia, Spondylitis, Peripheral neuralgias:, Diabetic neuropathy, Post-surgical pains
Adult Dose
Apply to affected area three/four times daily for 3-4 consecutive weeks and evaluate efficacy; efficacy decreased if used < 3 times daily; not to exceed 4 applications/day;
Child Dose
Safety & efficacy not established
Renal Dose
Administration
Apply a thin film of Capsaicin cream to affected area. A burning sensation may occur upon application, but generally disappears with regular use. Wash hands with soap and water after applying.
Contra Indications
Capsaicin cream is contraindicated for use on broken or irritated skin or known hypersensitivity to this medication.
Precautions
Capsaicin cream should not be applied to broken or irritated skin. Applied area should not be tightly bandaged. Do not get on mucous membranes and into eyes or on contact lenses. If this occurs, rinse the affected area thoroughly with water. Do not apply the cream on the heat treated area as this may increase the burning sensation.
Lactation: Unknown whether distributed in breast milk; do not apply to nipple or areola
Pregnancy-Lactation
Pregnancy Category: B
Lactation: Unknown whether distributed in breast milk; do not apply to nipple or areola
Interactions
Capsaicin, including topical use, may cause or exacerbate coughing associated with ACE inhibitor treatment and vice versa. If a severe cough develops in patients taking an ACE inhibitor and using capsaicin, 1 or both drugs may need to be discontinued.
Side Effects
Side effects of Capsaicin 0.025% topical :
>10%
Transient increased pain at application site (dissipates w/ continued use), Application site erythema (63%), Pain (42%)
1-10%
Nausea (5%), Vomiting (3%), Hypertension (2%), Dryness (2%), Swelling (2%), Pruritus (6%), Papules (6%), Edema (4%), Sinusitis (3%), Bronchitis (2%)
<1%
Exfoliation, Dizziness, Cough, Skin odor, Headache, Dysguesia
Mode of Action
Transient receptor potential vanilloid-1 (TRPV1) agonist; topical application causes initial TRPV1 stimulation that may cause pain, followed by pain relief by reduction in TRPV1-expressing nociceptive nerve endings
Note
Topicacin 25 mg/100 gm Cream generic name is Capsaicin 0.025% topical. Topicacin 25 mg/100 gm Cream is manufactured by Incepta Pharmaceuticals Ltd.Topicacin is availble in all over Bangladesh.
Mes BD drug index information on Topicacin Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.