Thianomin Injection

Thiamine Hydrochloride
25 mg/ml
Rephco Pharmaceuticals Ltd.
Pack size
Unite Price 2.60 BDT

Indications

Thianomin Injection is used for: Beriberi and Wernick's encephalopathy, neuritis associated with pregnancy and pellagra.

Adult Dose

Treatment and prophylaxis of mild chronic thiamine deficiency Adult: 10-25 mg daily in single or divided doses. Thiamine deficiency Adult: 1 tablet (100mg) daily, up to 300 mg daily. Wernicke-Korsakoff syndrome Adult: Initially, 100 mg by slow IV Inj over 10 min, then 50-100 mg/day IM or IV until the patient can take oral thiamine.

Child Dose

Thiamine deficiency 10-50 mg/day PO in divided doses Beriberi 10-25 mg IV/IM qDay (if crtically ill) or 10-50 mg/dose PO qDay for at least 2 weeks, THEN 5-10 mg/day PO for 1 month

Renal Dose

Administration

Should be taken with food.

Contra Indications

Hypersensitivity

Precautions

Parenteral admin. Increased daily requirements in pregnancy and lactation.

Pregnancy-Lactation

Pregnancy Category: A (injectable); C (if >RDA) Lactation: Safe

Interactions

May enhance the effect of neuromuscular blocking agents.

Side Effects

Side effects of Thiamine Hydrochloride : IV: Warm sensation, tingling, pruritus, pain, urticaria, weakness, sweating, nausea, restlessness, tightness of the throat, angioedema, respiratory distress, cyanosis, pulmonary oedema, GI bleeding, transient vasodilation and hypotension, vascular collapse. IM: Tenderness and induration. Potentially Fatal: Very rarely, fatal anaphylactic shock.

Mode of Action

Thiamine, a water soluble vitamin, combines with ATP to form thiamine pyrophosphate, an essential coenzyme in carbohydrate metabolism.

Note

Thianomin 25 mg/ml Injection generic name is Thiamine Hydrochloride. Thianomin 25 mg/ml Injection is manufactured by Rephco Pharmaceuticals Ltd.Thianomin is availble in all over Bangladesh. Mes BD drug index information on Thianomin Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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