Terbisol Cream

Terbinafine Topical
1%
NIPRO JMI Pharma Limited
Pack size 10gm tube
Unite Price 70.00 BDT

Indications

Terbisol Cream is used for: Tinea pedis, Tinea cruris, Tinea corporis, Dermatophytosis, Nail infections, Cutaneous candidiasis, Pityriasis versicolor

Adult Dose

Topical/Cutaneous As cream or spray Dermatophytosis Adult: Tinea Pedis: Apply to affected area BID until significant clinical improvement (no more than 4 weeks) Tinea Corporis & Cruris: Apply once daily, for 1 week, (no more than 4 weeks) Cutaneous candidiasis and pityriasis versicolor: Apply once or bid for 2 wk

Child Dose

Not FDA approved for peds

Renal Dose

Administration

Contra Indications

Hypersensitivity, active or chronic liver disease, lactation.

Precautions

Preexisting liver or renal impairment, pregnancy. Perform liver function tests prior to oral therapy. Lactation: not safe for nursing infants

Pregnancy-Lactation

Pregnancy Category: B Lactation: not safe for nursing infants

Interactions

Possible increase in levels in drugs metabolised by CYP450 2D6. Decreased terbinafine concentration with rifampicin; increased terbinafine concentration with cimetidine.

Side Effects

Side effects of Terbinafine Topical : 1-10% Burning, Contact dermatitis, Dryness, Exfoliation, Irritation, Pruritus, Rash, Irritation, Stinging Potentially Fatal: Liver failure, Stevens-Johnson syndrome, neutropaenia.

Mode of Action

Terbinafine causes fungal cell death by inhibiting squalene epoxidase, the main enzyme in sterol biosynthesis, resulting in ergosterol deficiency within fungal cell walls. It has fungicidal activity against dermatophytes and some yeast.

Note

Terbisol 1% Cream generic name is Terbinafine Topical. Terbisol 1% Cream is manufactured by NIPRO JMI Pharma LimitedTerbisol is availble in all over Bangladesh. Mes BD drug index information on Terbisol Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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