Sympres Tablet
Moxonidine
0.2mg
Eskayef Pharmaceuticals Ltd.
| Pack size | 30's pack |
|---|---|
| Unite Price | 10.00 BDT |
Indications
Sympres Tablet is used for:
Hypertension
Adult Dose
Oral
Hypertension
Adult: 200 mcg once daily, increase if necessary after 3 wk to 400 mcg daily as single or in 2 divided doses. If necessary, after a further 3 wk, increase to 600 mcg daily in 2 divided doses. Max: 600 mcg daily.
Child Dose
Renal Dose
Renal impairment:
CrCl (ml/min) Dosage Recommendation
30-60 Single dose should not exceed 200 mcg. Max daily dose 400 mcg.
<30 Avoid
Administration
May be taken with or without food.
Contra Indications
Conduction disorders; bradycardia; severe arrhythmias; severe heart failure; severe ischaemic heart disease; history of angioedema; severe liver or renal impairment; Raynaud's syndrome; intermittent claudication; epilepsy; depression; Parkinson's disease; glaucoma. Pregnancy and lactation.
Precautions
Renal impairment; avoid abrupt withdrawal (if concomitant treatment with ?-blocker has to be stopped, discontinue ?-blocker first, then moxonidine after few days).
Pregnancy-Lactation
Interactions
Additive effects with other antihypertensives; may increase sedative effects of benzodiazepines. Effects may be antagonised by TCAs.
Side Effects
Side effects of Moxonidine :
Dry mouth; headache; fatigue; dizziness; nausea; sleep disturbances; asthenia; vasodilatation; skin reactions; constipation; depression; anxiety; anorexia; parotid pain; vivid dreams; impotence and loss of libido; urinary retention or incontinence; slight orthostastic hypotension; fluid retention.
Mode of Action
Moxonidine is a centrally-acting antihypertensive. It acts in the brainstem through stimulation of central imidazoline receptors to reduce sympathetic tone. Moxonidine also has a low affinity for alpha2-adrenoceptors.
Note
Sympres 0.2mg Tablet generic name is Moxonidine. Sympres 0.2mg Tablet is manufactured by Eskayef Pharmaceuticals Ltd.Sympres is availble in all over Bangladesh.
Mes BD drug index information on Sympres Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.