Suxen Gel

Naproxen 10% Topical
Supreme Pharmaceuticals Ltd.
Pack size 15gm tube
Unite Price 62.00 BDT

Indications

Suxen Gel is used for: Rheumatoid arthritis, Osteoarthritis, Ankylosing spondylitis, Mild to moderate pain, Tendonitis, Acute musculoskeletal disorders, Bursitis

Adult Dose

Topica Adult: Apply Naproxen gel 2-6 times a day as required.

Child Dose

Renal Dose

Administration

Contra Indications

Hypersensitivity. Aspirin or NSAID allergy. Perioperative pain in the setting of CABG surgery. Pregnancy (3rd trimester)

Precautions

Pre-existing CV risk factors or disease e.g. fluid retention, CHF, hypertension. History of GI disease (bleeding or ulcers). Other forms of asthma. Hepatic impairment; closely monitor patients with any abnormal LFT. Renal impairment. Elderly. Lactation.

Pregnancy-Lactation

Pregnancy category: C; D in 3rd trimester or near delivery.

Interactions

May enhance methotrexate toxicity. Reduced BP response to ACE inhibitors or angiotensin II receptor antagonists. Increased risk of serious GI events (e.g. ulcer) w/ aspirin. Increased risk of GI bleeding w/ warfarin. May reduce the natriuretic effects of furosemide or thiazide diuretics. May increase serum lithium concentrations and reduce renal lithium clearance. Delayed absorption w/ antacids, colestyramine or sucralfate. May interfere w/ the antihypertensive effects of ?-blockers (e.g. propranolol). May increase serum levels w/ probenecid.

Side Effects

Side effects of Naproxen 10% Topical : Oedema, palpitation, dizziness, drowsiness, headache, light headedness, vertigo, pruritus, skin eruption, ecchymosis, purpura, rash, fluid retention, abdominal pain, constipation, nausea, heartburn, diarrhoea, dyspepsia, stomatitis, flatulence, gross bleeding/perforation, indigestion, ulcers, vomiting, abnormal renal function, haemolysis, anaemia, increased bleeding time, elevated LFTs, visual disturbances, tinnitus, hearing disturbances, dyspnoea, diaphoresis, thirst. Potentially Fatal: Anaphylactic/anaphylactoid reactions. Exfoliative dermatitis, Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN).

Mode of Action

Naproxen, a propionic acid derivative, is a prototypical NSAID. It reversibly inhibits the cyclooxygenase-1 and -2 (COX-1 and -2) enzymes, thus resulting in reduced synthesis of prostaglandin precursors. It can inhibit platelet aggregation, has anti-inflammatory, analgesic and antipyretic actions.

Note

Suxen Gel generic name is Naproxen 10% Topical. Suxen Gel is manufactured by Supreme Pharmaceuticals Ltd.Suxen is availble in all over Bangladesh. Mes BD drug index information on Suxen Gel is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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