Steson Cream
Clobetasone butyrate 0.05% Topical
50 mg/100 gm
Navana Pharmaceuticals Ltd.
| Pack size | |
|---|---|
| Unite Price | 41.00 BDT |
Indications
Steson Cream is used for:
Inflammatory skin disorders, Eczema, dermatitis, atopic eczema, photodermatitis, otitis externa, primary irritant & allergic dermatitis (napkin rash), prurigo nodularis, seborrhoeic dermatitis, insect bite reactions.
Adult Dose
Topical/Cutaneous
Corticosteroid-responsive dermatoses
Adult: Use as 0.05% cream or ointment to be applied thinly once or bid on affected areas.
This medicine should not be used every day for more than 4 weeks at a time.
Child Dose
Renal Dose
Administration
Wash hands and dry them
Squeeze out the correct amount of cream onto index finger.
Half a fingertip will cover a patchnof skin the same size as the palm of hand.
Gently rub the cream into the skin area that are treating.
Wash hands again (unless it is your hands you are treating).
Contra Indications
Pregnancy (in high doses). Presence of acute infections. Treatment of rosacea; leg ulcers; acne vulgaris; widespread plaque psoriasis. Child <1 yr.
Precautions
May be absorbed in sufficient amounts to cause systemic effects when applied topically to large areas, broken skin or under occlusive dressings. Peptic ulcer, osteoporosis, psychoses or severe psychoneuroses. Not to be used indiscriminately for pruritus. CHF or hypertension. Diabetes mellitus, epilepsy, glaucoma, infectious diseases, ocular herpes simplex, chronic renal failure and uraemia. Active or doubtfully quiescent tuberculosis. Local treatment of eye disorders. Elderly. Prolonged use on the face.
Pregnancy-Lactation
Pregnancy
Safety data on clobetasol in pregnant woman is not available
Published data report a significantly increased risk of low birthweight with the use of greater than 300 grams of potent or very potent topical corticosteroid during a pregnancy
Advise pregnant women of the potential risk to a fetus and to use clobetasol on the smallest area of skin and for the shortest duration possible
In animal reproduction studies, increased malformations (eg, cleft palate and skeletal abnormalities), were observed after SC administration of clobetasol to pregnant mice and rabbits
Lactation
No information is available regarding the presence of clobetasol in breast milk or its effects on the breastfed infant or on milk production
Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects
Unknown whether topical administration of clobetasol could result in sufficient systemic absorption to produce detectable quantities in human milk
To minimize potential exposure to the breastfed infant via breast milk, use clobetasol on the smallest area of skin and for the shortest duration possible while breastfeeding
Advise breastfeeding women to avoid applying clobetasol directly to the nipple and areola to prevent direct infant exposure
Interactions
Side Effects
Side effects of Clobetasone butyrate 0.05% Topical :
Local atrophic changes; pigmentation changes & hypertrichosis. Increased liability to infection. Infections may be masked. Acute adrenal insufficiency. Growth retardation in child. Cushingoid symptoms. Amenorrhoea, hyperhidrosis, skin thinning,
Mode of Action
Clobetasone butyrate is classed as a moderately potent topical corticosteroid. Corticosteroids decrease inflammation by stabilizing leukocyte lysosomal membranes, preventing release of destructive acid hydrolases from leukocytes; inhibiting macrophage accumulation in inflamed areas; reducing leukocyte adhesion to capillary endothelium; reducing capillary wall permeability and edema formation; decreasing complement components; antagonizing histamine activity and release of kinin from substrates; and reducing fibroblast proliferation, collagen deposition, and subsequent scar tissue formation.
Note
Steson 50 mg/100 gm Cream generic name is Clobetasone butyrate 0.05% Topical. Steson 50 mg/100 gm Cream is manufactured by Navana Pharmaceuticals Ltd.Steson is availble in all over Bangladesh.
Mes BD drug index information on Steson Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.