Indications
Stamurine Tablet is used for:
Beriberi and Wernick's encephalopathy, neuritis associated with pregnancy and pellagra.
Adult Dose
Treatment and prophylaxis of mild chronic thiamine deficiency
Adult: 10-25 mg daily in single or divided doses.
Thiamine deficiency
Adult: 1 tablet (100mg) daily, up to 300 mg daily.
Wernicke-Korsakoff syndrome
Adult: Initially, 100 mg by slow IV Inj over 10 min, then 50-100 mg/day IM or IV until the patient can take oral thiamine.
Child Dose
Thiamine deficiency
10-50 mg/day PO in divided doses
Beriberi
10-25 mg IV/IM qDay (if crtically ill) or 10-50 mg/dose PO qDay for at least 2 weeks, THEN
5-10 mg/day PO for 1 month
Renal Dose
Administration
Should be taken with food.
Contra Indications
Hypersensitivity
Precautions
Parenteral admin. Increased daily requirements in pregnancy and lactation.
Pregnancy-Lactation
Pregnancy Category: A (injectable); C (if >RDA)
Lactation: Safe
Interactions
May enhance the effect of neuromuscular blocking agents.
Side Effects
Side effects of Thiamine Hydrochloride :
IV: Warm sensation, tingling, pruritus, pain, urticaria, weakness, sweating, nausea, restlessness, tightness of the throat, angioedema, respiratory distress, cyanosis, pulmonary oedema, GI bleeding, transient vasodilation and hypotension, vascular collapse.
IM: Tenderness and induration.
Potentially Fatal: Very rarely, fatal anaphylactic shock.
Mode of Action
Thiamine, a water soluble vitamin, combines with ATP to form thiamine pyrophosphate, an essential coenzyme in carbohydrate metabolism.
Note
Stamurine 100mg Tablet generic name is Thiamine Hydrochloride. Stamurine 100mg Tablet is manufactured by Standard Laboratories Ltd.Stamurine is availble in all over Bangladesh.
Mes BD drug index information on Stamurine Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.