Spasmin Tablet

Hyoscine Butyl Bromide
10mg
Doctor's Chemicals Works Ltd.
Pack size 100's Pack
Unite Price 1.54 BDT

Indications

Spasmin Tablet is used for: Gastrointestinal tract spasm, Abdominal pain, Genitourinary spasm

Adult Dose

Oral Gastrointestinal tract spasm; Genitourinary spasm Adult: 20 mg 4 times daily. Parenteral Gastrointestinal tract spasm; Genitourinary spasm Adult: 20 mg IM/IV repeated after 30 min if needed. Max Dosage: 100 mg daily.

Child Dose

Oral Gastrointestinal tract spasm; Genitourinary spasm Child: 6-12 yr: 10 mg tid.

Renal Dose

Administration

Contra Indications

Narrow-angle glaucoma, acute haemorrhage, paralytic ileus, tachycardia due to cardiac insufficiency, myasthenia gravis.

Precautions

Hepatic/renal disease, pyloric stenosis, urinary retention, prostatic hyperplasia, psychosis, seizure disorders, ulcerative colitis, coronary artery disease, tachyarrhythmias, heart failure, hypertension. Elderly, children, pregnancy, lactation.

Pregnancy-Lactation

Interactions

Additive sedative effects with alcohol or other CNS depressants. Reduced effects with acetylcholinesterase inhibitors (donepezil, galantamine, rivastigmine, tacrine). Potentially Fatal: Effect potentiated by other anticholinergic drugs and TCAs.

Side Effects

Side effects of Hyoscine Butyl Bromide : Flushing, postural hypotension, tachycardia, fibrillation. Rarely psychotic reactions. Dizziness, drowsiness, fatigue, headache, memory loss. Dry skin, erythema, increased sensitivity to light, rash. Bloatedness, constipation, dry throat, dysphagia, nausea, vomiting, xerostomia. Dysuria, urinary retention. Tremor, weakness. Impaired accommodation, blurred vision, cycloplegia, dryness, narrow-angle glaucoma, increased intraocular pain, itching, photophobia, pupil dilation. Dry nose. Decreased diaphoresis, heat intolerance. Ophthalmic: Somnolence, dermatitis, oedema, exudate, follicular conjunctivitis, increased IOP, local irritation, photophobia, vascular and respiratory congestion. Potentially Fatal: CNS depression, coma, circulatory and respiratory failure.

Mode of Action

Hyoscine competitively blocks muscarinic receptors and has central and peripheral actions. It relaxes smooth muscle and reduces gastric and intestinal motility.

Note

Spasmin 10mg Tablet generic name is Hyoscine Butyl Bromide. Spasmin 10mg Tablet is manufactured by Doctor's Chemicals Works Ltd.Spasmin is availble in all over Bangladesh. Mes BD drug index information on Spasmin Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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