Retigel Gel
Isotretinoin 0.05% Topical
0.05 gm/100 gm
Unimed & Unihealth Manufacturers Ltd.
| Pack size | 20gm tube |
|---|---|
| Unite Price | 200.00 BDT |
Indications
Retigel Gel is used for:
Acne
Adult Dose
Topical/Cutaneous
Acne
Adult: As 0.05% gel: Apply sparingly once or twice daily. Effect is observed w/in 6-8 wk of treatment.
Child Dose
Renal Dose
Administration
Contra Indications
Pregnancy, lactation.
Precautions
Preexisting or predisposition to hypertriglyceridaemia (e.g. DM, obesity or increased alcohol intake). Monitor triglyceride levels. Monitor blood lipids and LFTs at wkly or bi-wkly intervals. Monitor blood glucose in known or suspected DM patients. Genetic predisposition for age-related osteoporosis, history of childhood osteoporosis, osteomalacia or other bone metabolism disorders. Anorexia nervosa. History of psychiatric disorder. May impair night vision. Avoid wax epilation and skin resurfacing procedures for at least 6 mth. Avoid prolonged exposure to UV light or sunlight. Discontinue if hearing impairment, abdominal pain, rectal bleeding, severe diarrhoea or adverse ocular effects occur. Patient should not donate blood during therapy and for at least 1 mth following drug discontinuation.
Pregnancy-Lactation
Interactions
Additive toxicity with vitamin A or its derivatives. Decreased efficacy of microdosed progesterone (use 2 forms of contraception). May increase risk of bone loss with phenytoin. May increase risk of osteoporosis with systemic corticosteroids. Reduces plasma levels of carbamazepine.
Potentially Fatal: Increased risk of pseudotumor cerebri with tetracyclines.
Side Effects
Side effects of Isotretinoin 0.05% Topical :
Dryness of mucous membranes, dryness of skin with scaling, fragility, erythema, cheilitis, pruritus, epistaxis, conjunctivitis, dry sore mouth and palmo-plantar exfoliation. Corneal opacities, dry eyes, visual disturbances, skeletal hyperostosis and musculoskeletal symptoms. Elevation of serum triglycerides, LFTs, ESR and blood glucose. Hair thinning, photosensitivity, changes in skin pigmentation, paronychia. GI disturbances, hepatitis. Headache, drowsiness, sweating, mood changes, psychotic symptoms, depression, suicidal tendencies, benign intracranial hypertension, seizures. Vasculitis, hypersensitivity reactions, IBS.
Potentially Fatal: Anaphylaxis. Haemorrhagic pancreatitis.
Mode of Action
Isotretinoin is a synthetic retinoid which reduces sebaceous gland size and sebum production. It also regulates cell proliferation and differentiation.
Note
Retigel 0.05 gm/100 gm Gel generic name is Isotretinoin 0.05% Topical. Retigel 0.05 gm/100 gm Gel is manufactured by Unimed & Unihealth Manufacturers Ltd.Retigel is availble in all over Bangladesh.
Mes BD drug index information on Retigel Gel is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.