Indications
Rapilief Capsule is used for:
Treating the signs and symptoms of enlarged prostate (benign prostatic hyperplasia [BPH]).
Adult Dose
Benign Prostatic Hyperplasia
Adults
PO 8 mg once daily with a meal.
Hepatic Impairment
Mild-to-moderate impairment (Child-Pugh class A or B): Dose adjustment not necessary
Severe Impairment: (Child-Pugh class C): Contraindicated (not studied)
Child Dose
Renal Dose
Renal Impairment
CrCl <50 mL/min: Dose adjustment not necessary
CrCl 30-50 mL/min: 4 mg PO qDay
CrCl <30 mL/min: Contraindicated
Administration
Contra Indications
Hypersensitivity.
Precautions
Impaired hepatic & renal function. Start treatment w/ a low dose (2 mg/dose).
Pregnancy-Lactation
Pregnancy Category: B; not indicated in women
Lactation: Unknown if distributed in breast milk; not indicated in women
Interactions
Ketoconazole, digoxin.
Side Effects
Side effects of Silodosin :
>10%
Retrograde ejaculation (28%)
1-10%
Diarrhea (3%), Headache (2%), Insomnia ((1-2%), Dizziness (3%), Orthostatic hypotension (3%; increased in patients >65 years), Nasopharyngitis (2%), Nasal congestion (2%), Sinusitis (1-2%)
Mode of Action
Selectively blocks postsynaptic alpha-1 adrenoreceptors located in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra.
Note
Rapilief 8mg Capsule generic name is Silodosin. Rapilief 8mg Capsule is manufactured by Nuvista Pharma LtdRapilief is availble in all over Bangladesh.
Mes BD drug index information on Rapilief Capsule is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.