Prefol Tablet

Folic Acid
5mg
Unimed & Unihealth Manufacturers Ltd.
Pack size 100's Pack
Unite Price 0.35 BDT

Indications

Prefol Tablet is used for: Anemia, Nutritional supplement, Folic acid deficiency, Megaloblastic anemia, Neural tube defect

Adult Dose

Oral Folate-deficient megaloblastic anaemia Adult: 5 mg daily for 4 mth, up to 15 mg daily in malabsorption states. Continued dosing at 5 mg every 1-7 days may be needed in chronic haemolytic states, depending on the diet and rate of haemolysis. Prophylaxis of megaloblastic anaemia in pregnancy Adult: 0.2-0.5 mg daily. Prophylaxis of neural tube defect in pregnancy Adult: 4 or 5 mg daily starting before pregnancy and continued through the 1st trimester. As supplement for women of child-bearing potential Adult: 0.4 mg daily.

Child Dose

Folic Acid Deficiency Infants: 15 mcg/kg/day or 50 mcg/day 1-10 years: 1 mg/day initially, then 0.1-0.4 mg/day

Renal Dose

Administration

May be taken with or without food.

Contra Indications

This product is contraindicated in patients with a known hypersensitivity to any of the ingredients. Folic Acid is contraindicated in untreated cobalamine deficiency.

Precautions

Treatment resistance may occur in patients with depressed haematopoiesis, alcoholism, deficiencies of other vitamins. Neonates. Lactation: Drug enters breast milk; safe for nursing

Pregnancy-Lactation

Pregnancy category: A Lactation: Drug enters breast milk; safe for nursing

Interactions

Antiepileptics, oral contraceptives, anti-TB drugs, alcohol, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides may result to decrease in serum folate contrations. Decreases serum phenytoin concentrations.

Side Effects

Side effects of Folic Acid : Bronchospasm, Erythema, Malaise, Pruritus, Rash, Slight flushing

Mode of Action

Folic acid: Required for nucleoprotein synthesis and the maintenance of normal erythropoiesis; folic acid is converted in the liver and plasma to its metabolically active form, tetrahydrofolic acid, by dihydrofolate reductase; prevents neural tube defects in women of childbearing potential and higher doses required during pregnancy.

Note

Prefol 5mg Tablet generic name is Folic Acid. Prefol 5mg Tablet is manufactured by Unimed & Unihealth Manufacturers Ltd.Prefol is availble in all over Bangladesh. Mes BD drug index information on Prefol Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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