Polymix Eye Ointment
Bacitracin Zinc + Polymixin B Eye prep
500 IU + 10000 IU/gm
Opso Saline Ltd.
| Pack size | 5gm tube |
|---|---|
| Unite Price | 35.13 BDT |
Indications
Polymix Eye Ointment is used for:
Bacterial ocular infections
Adult Dose
Adult: Ophth Ocular infections; Prevention of ocular infection following surgical procedure:
Apply ½ inch 3-4 hrly for acute infections or 2-3 times/day for mild-to-moderate infections for 7-10 days.
Treatment should be continued for another 2 days after the eye has apparently recovered.
Child Dose
Child: Apply ½ inch ribbon in the affected eye(s) every 3-4 hr for acute infections or 2-3 times/day for mild-to-moderate infections for 7-10 days. Treatment should be continued for another 2 days after the eye has apparently recovered.
Renal Dose
Administration
Contra Indications
Hypersensitivity.
Precautions
Ointment may blur vision. Prolonged use of the antibacterial preparation may cause overgrowth of non-susceptible organisms, including fungi. Pregnancy and lactation.
Lactation: Excretion in breast milk unknown; use caution
Pregnancy-Lactation
Pregnancy Category: C
Lactation: unknown if distributed in breast milk
Interactions
Bacitracin Zinc: Increased risk of nephrotoxicity when used with other nephrotoxic drugs. May enhance the action of neuromuscular-blocking agents.
Polymixin B: Potentially Fatal: Additive neurotoxic or nephrotoxic effect w/ bacitracin, streptomycin, neomycin, kanamycin, gentamicin, tobramycin, amikacin, cephaloridine, paromomycin, viomycin, colistin. Increased risk of resp paralysis w/ neuromuscular blockers (e.g. anaesthetics, muscle relaxants).
Side Effects
Side effects of Bacitracin Zinc + Polymixin B Eye prep :
<1%
Allergic contact dermatitis, Conjunctival erythema, Swelling, Itching, Burning
Mode of Action
Bacitracin, inhibits bacterial cell wall synthesis and is active against many gram-positive bacteria (e.g. staphylococci, streptococci, corynebacteria and clostridia) and some gram-negative species (e.g. Neisseria and Haemophilus influenzae).
They are often found in combinations in topical preparations as broad spectrum antibacterial agents. Polymyxin B disrupts the bacterial cytoplasmic membrane of mostly gm-ve organisms allowing leakage of intracellular constituents by binding to membrane phospholipids.
Note
Polymix 500 IU + 10000 IU/gm Eye Ointment generic name is Bacitracin Zinc + Polymixin B Eye prep. Polymix 500 IU + 10000 IU/gm Eye Ointment is manufactured by Opso Saline Ltd.Polymix is availble in all over Bangladesh.
Mes BD drug index information on Polymix Eye Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.