Pmec Cream
Pimecrolimus 1% Topical
1%
Navana Pharmaceuticals Ltd.
| Pack size | 10 g |
|---|---|
| Unite Price | 1,000.00 BDT |
Indications
Pmec Cream is used for:
Atopic dermatitis, Eczema
Adult Dose
Topical/Cutaneous
Atopic dermatitis
Adult: As 1% cream: Apply a thin layer onto the affected areas bid. Stop treatment if there is no improvement after 6 wk or if there is worsening of eczema.
Hepatic impairment: Dosage reduction is necessary.
Child Dose
Topical/Cutaneous
Atopic dermatitis
Child: >2 yr: Apply a thin layer of 1% cream onto the affected areas bid. Stop treatment if there is no improvement after 6 wk or if there is worsening of eczema.
Hepatic impairment: Dosage reduction is necessary.
Renal Dose
Renal impairment: Dosage reduction is necessary.
Administration
Contra Indications
Hypersensitivity; children <2 yr; immunocompromised patients. Patients with Netherton's syndrome.
Precautions
Avoid use in areas affected by active, cutaneous viral infections. Avoid contact with the eyes and mucous membranes. Immunosuppression may increase risk of lymphoma and other malignancies. Limit exposure to sunlight or other UV light. Mild to moderate sensation of warmth and/or burning may occur at the treatment site within 1-5 days of initiation. Safety of usage beyond 1 yr is not established. Renal or hepatic impairment. Monitor renal, hepatic, cardiac and visual functions, BP, serum glucose and electrolytes regularly. Pregnancy, lactation.
Lactation: not known whether distributed in breast milk; may cause unwanted effects in nursing babies
Pregnancy-Lactation
Pregnancy Category: C
Lactation: not known whether distributed in breast milk; may cause unwanted effects in nursing babies
Interactions
Inhibitors of cytochrome P450 3A4 isoenzyme in patients with widespread and/or erythrodermic disease.
Potentially Fatal: Increased risk of infections when used with live vaccines.
Side Effects
Side effects of Pimecrolimus 1% Topical :
>10%
Burning sensation (2-26%), Headache (7-25%), Fever (1-13%), Nasopharyngitis (8-27%), Cough (2-16%), Bronchitis (<11%), Upper respiratory tract infection (4-19%)
<1%
Basal cell carcinoma of skin, Malignant melanoma, Squamous cell carcinoma, Malignant lymphoma, Septic arthritis, Skin discoloration, Eczema, Flushing, Ocular irritation
Frequency Not Defined
Skin infection, Rash, Application site pain, Paraesthesia, Desquamation, Dryness
Mode of Action
Pimecrolimus is a macrolactam and is a derivative of ascomycin. It is an immunosuppressant which inhibits the activation of T-cells and prevents the release of inflammatory mediators from mast cells. It is used for the short term or intermittent long term treatment for mild to moderate atopic eczema.
Note
Pmec 1% Cream generic name is Pimecrolimus 1% Topical. Pmec 1% Cream is manufactured by Navana Pharmaceuticals Ltd.Pmec is availble in all over Bangladesh.
Mes BD drug index information on Pmec Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.