Phoscon Tablet

Ferric Citrate
210mg
Navana Pharmaceuticals Ltd.
Pack size 30's Pack
Unite Price 25.00 BDT

Indications

Phoscon Tablet is used for: Hyperphosphatemia, Iron Deficiency Anemia

Adult Dose

Hyperphosphatemia in Chronic Kidney Disease on Dialysis The recommended starting dose is 2 tablets orally 3 times per day with meals. Monitor serum phosphorus levels and titrate the dose in decrements or increments of 1 to 2 tablets per day as needed to maintain serum phosphorus at target levels, up to a maximum dose of 12 tablets daily. Iron Deficiency Anemia in Chronic Kidney Disease Not on Dialysis The recommended starting dose is 1 tablet orally 3 times per day with meals. Titrate the dose of as needed to achieve and maintain hemoglobin at target levels, up to a maximum dose of 12 tablets daily. For Iron Deficiency Anemia: 120-240mg elemental Fe3+ iron per day immediately after meal for 7 weeks

Child Dose

Renal Dose

Administration

Take with meals Do not chew or crush tablets because tablets may cause discoloration of mouth and teeth

Contra Indications

Contraindicated in patients with iron overload syndromes (e.g., hemochromatosis)

Precautions

Iron overload: Monitor ferritin and TSAT. Patients may require a reduction in dose or discontinuation of intravenous iron Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6 years of age. Keep this product out of reach of children.

Pregnancy-Lactation

Pregnancy There are no available data regarding use in pregnant women An overdose of iron in pregnant women may carry a risk for spontaneous abortion, gestational diabetes, and fetal malformation Lactation There are no human data regarding the effect in human milk, the effects on the breastfed child, or the effects on milk production Data from rat studies have shown the transfer of iron into milk by divalent metal transporter-1 (DMT-1) and ferroportin-1 (FPN-1); therefore, there is a possibility of infant exposure The development and health benefits of breastfeeding should be considered along with the mother’s clinical need for the drug and any potential adverse effects on the breastfed child or from the underlying maternal condition

Interactions

Doxycycline and Ciprofloxacin has to be separated from drugs.

Side Effects

Side effects of Ferric Citrate : >10% Discolored feces (22%) Diarrhea (21%) Constipation (8-18%) Nausea (10-11%) 1-10% Vomiting (7%) Cough (6%) Hyperkalemia (5%) Abdominal pain (5%)

Mode of Action

Hyperphosphatemia in CKD on dialysis Phosphate binder; ferric iron binds dietary phosphate in the GI tract and precipitates as ferric phosphate, which is insoluble and is excreted in the feces By binding phosphate in the GI tract and decreasing absorption, ferric citrate lowers the phosphate concentration in the serum Iron deficiency anemia in CKD not on dialysis Ferric iron is reduced from the ferric to the ferrous form by ferric reductase in the GI tract After transport through the enterocytes into the blood, oxidized ferric iron circulates bound to the plasma protein transferrin, and can be incorporated into hemoglobin

Note

Phoscon 210mg Tablet generic name is Ferric Citrate. Phoscon 210mg Tablet is manufactured by Navana Pharmaceuticals Ltd.Phoscon is availble in all over Bangladesh. Mes BD drug index information on Phoscon Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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