Pevitin Cream
Econazole Nitrate 1% + Triamcinolone Acetonide 0.1 Topical
(10 mg + 1 mg)/gm
Square Pharmaceuticals Ltd.
| Pack size | 15gm tube |
|---|---|
| Unite Price | 65.00 BDT |
Indications
Pevitin Cream is used for:
Steroid-responsive inflammatory dermatoses, Tinea pedis, Tinea cruris, Tinea corporis, Pityriasis versicolor, Cutaneous candidiasis, Onychomycoses
Adult Dose
Topical
Adults: Apply 2-3 times daily to the affected area and rub on the skin gently with the finger.
Continue the applications for 14 days
Child Dose
Renal Dose
Administration
Contra Indications
Not to be used in the treatment of tuberculous lesions and viral diseases of the skin (herpes, vaccinia, varicella).True hypersensitivity.
Precautions
Hypersensitivity has rarely been recorded. If it occurs, application of the product should be discontinued. The infected area should be kept clean and dry during treatment.
Pregnancy-Lactation
Interactions
Econazole: Theoretical potential for compd metabolized by CYP3A4/2C9, oral anticoagulants eg warfarin & acenocoumarol.
Triamcinolone: Lowering of plasma salicylates levels. Increased risk of GI bleeding and ulceration with NSAIDs. Antagonised blood glucose-lowering effects of the antidiabetics. Increased risk of hyperkalaemia with amphotericin B, beta-blockers, potassium-depleting diuretics, theophylline. Increased clearance of the triamcinolone with ciclosporin, carbamazepine, phenytoin, barbiturate, rifampicin. Infections may develop if given with live vaccines.
Side Effects
Side effects of Econazole Nitrate 1% + Triamcinolone Acetonide 0.1 Topical :
Rarely, transient local mild irritation, itching & redness may occur immediately after application. Econazole has minimal allergenic effect and is well tolerated, even by delicate skin. Adrenal suppression on long term continuous topical steroid therapy may occur, particularly in infants or children, or when occlusive dressings are applied. It should be noted that an infant's napkin may act as an occlusive dressing.
Mode of Action
Econazole modifies the permeability of cell wall membrane in fungi; may interfere w/ RNA and protein synthesis, and lipid metabolism.
Triamcinolone has mainly glucocorticoid activity. It suppresses the migration of polymorphonuclear leukocytes and reduces capillary permeability thereby decreasing inflammation.
Note
Pevitin (10 mg + 1 mg)/gm Cream generic name is Econazole Nitrate 1% + Triamcinolone Acetonide 0.1 Topical. Pevitin (10 mg + 1 mg)/gm Cream is manufactured by Square Pharmaceuticals Ltd.Pevitin is availble in all over Bangladesh.
Mes BD drug index information on Pevitin Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.