Pentocil Suspension

Aluminium Hydroxide + Magnesium Hydroxide
15g/100ml
Albion Laboratories Ltd.
Pack size 200 ml
Unite Price 30.50 BDT

Indications

Pentocil Suspension is used for: Heartburn, Reflux oesophagitis, Hyperacidity, Peptic ulcer, Constipation, Indigestion

Adult Dose

Adult: PO Gastric Hyperacidity, Heartburn: Up to 1 g/day. Hyperphosphataemia in chronic renal failure Up to 10 g/day in divided doses w/ meals. 10-20 mL PO between meals & qHS

Child Dose

Renal Dose

Administration

May be taken with or without food.

Contra Indications

Hypersensitivity to aluminium salts.

Precautions

Chronic renal impairment; CHF; oedema; cirrhosis and low Na diets; patients with recent GI haemorrhage. Administer 2-3 hrs before/after another medication to minimise drug interactions. Pregnancy and lactation. Lactation: excretion in milk unknown; use caution

Pregnancy-Lactation

Pregnancy Category: C Lactation: excretion in milk unknown; use caution

Interactions

Aluminium Hydroxide: Enhanced absorption with citrates or ascorbic acid. Decreases absorption of allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine. Magnesium Hydroxide: Decreases absorption of tetracyclines and biphosphonates. Separate administration of these and other drugs by around 2 hr.

Side Effects

Side effects of Aluminium Hydroxide + Magnesium Hydroxide : >10% Aluminum oxide, Chalky taste, Constipation, Fecal impaction, Stomach cramps Frequency Not Defined Aluminum oxide, Nausea, Vomiting, Aluminum intoxication, Hypophosphatemia, Osteomalacia, Magnesium oxide, Diarrhea, Hypermagnesemia

Mode of Action

Alumunium hydroxide acts on the HCl in the stomach by neutralization, forming aluminium chloride salt and water. Magnesium hydroxide increases peristaltic activity causing osmotic retention of fluids, thus resulting in bowel evacuation. It also reduces stomach acid by reacting with hydrochloric acid to form Mg chloride.

Note

Pentocil 15g/100ml Suspension generic name is Aluminium Hydroxide + Magnesium Hydroxide. Pentocil 15g/100ml Suspension is manufactured by Albion Laboratories Ltd.Pentocil is availble in all over Bangladesh. Mes BD drug index information on Pentocil Suspension is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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