Oxima 300 Acucap Inhalation Capsule

Indacaterol

300mcg

ACI Limited

Pack size	10's Pack
Unite Price	65.00 BDT

Indications

Oxima 300 Acucap Inhalation Capsule is used for: Indacaterol Maleate is indicated for maintenance bronchodilator treatment of airflow obstruction in adult patients with, chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.

Adult Dose

Inhalation Maintenance therapy in chronic obstructive pulmonary disease Adult: As inhal cap: Inhale 75-150 mcg once daily using inhaler. Max: 300 mcg once daily. Hepatic impairment No dose adjustment is required for patients with mild and moderate hepatic impairment. There are no data available for use of Onbrez Breezhaler in patients with severe hepatic impairment.

Child Dose

Safety and efficacy not established

Renal Dose

Renal impairment No dose adjustment is required for patients with renal impairment.

Administration

Contra Indications

All LABA are contraindicated in patients with asthma without use of a long-term asthma control medication. Indacaterol is not indicated for the treatment of asthma. Indacaterol is contraindicated in patients with a history of hypersensitivity to indacaterol or to any of the ingredients.

Precautions

Not intended for treatment of asthma and acute deterioration of COPD. Patient w/ acutely deteriorating COPD, thyrotoxicosis, seizure disorders, DM, hypokalaemia, CV disorders esp coronary insufficiency, cardiac arrhythmias or HTN. Pregnancy and lactation. Lactation: Unknown whether distributed in human breast milk; use caution

Pregnancy-Lactation

Pregnancy Category: C Beta-agonists are known to inhibit uterine contractility Lactation: Unknown whether distributed in human breast milk; use caution

Interactions

Potentiated adverse effects w/ other sympathomimetic agents; possible hypokalaemic effect w/ methylxanthine derivatives, steroids or non-K-sparing diuretics. Other long-acting beta2-adrenergic agonists or medicinal products containing long-acting beta2-adrenergic agonists. Inhibition of the key contributors of indacaterol clearance, CYP3A4 and P-gp.

Side Effects

Side effects of Indacaterol : >10% Post-inhalation cough (24% compared with 7% on placebo) 1-10% Cough (6.5%), Nasopharyngitis (5.3%), Headache (5.1%), Nausea (2.4%), Oropharyngeal pain (2.2%) Potentially Fatal: Asthma-related deaths.

Mode of Action

Indacaterol is a long acting β2-adrenergic agonist. It relaxes the bronchial smooth muscle by selective action on β2-receptor which acts locally in the lungs and w/ little effect on heart rate.

Note

Oxima 300 Acucap 300mcg Inhalation Capsule generic name is Indacaterol. Oxima 300 Acucap 300mcg Inhalation Capsule is manufactured by ACI LimitedOxima 300 Acucap is availble in all over Bangladesh. Mes BD drug index information on Oxima 300 Acucap Inhalation Capsule is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Indacaterol :

Dry powder inhalation capsule

Onbrez Breezhaler ^150mg

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Dry Powder Inhalation Capsule

Onbrez Breezhaler ^300mg

Novartis (Bangladesh) Ltd.

Dry Powder Inhalation Capsule

Onriva ^75mcg

Beximco Pharmaceuticals Ltd.

DPI Capsule

Caterol 150 ^{150 mcg}

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DPI Capsule

Caterol 75 ^75mcg

Incepta Pharmaceuticals Ltd.