Indications
Orotifen Tablet is used for:
Allergic conjunctivitis, Allergic conditions, Asthma prophylaxis
Adult Dose
Oral
Allergic conditions; Asthma prophylaxis
Adult: 1 mg bid up to 2 mg bid, as needed. Alternatively, 0.5-1 mg at night for the 1st few days of treatment to minimise drowsiness.
Child Dose
Allergic conditions; Asthma prophylaxis
Tablet
Child: 6 mth to 3 yr: 0.5 mg bid;
>3 yr: 1 mg bid.
Syrup:
6 months to 3 years:
0.25 ml / kg body weight, twice daily (Once in the morning & once in the evening).
Renal Dose
Administration
Should be taken with food.
Contra Indications
Acute asthma attack.
Precautions
May impair tasks requring mental alertness e.g. driving or operating machinery. History of epilepsy. Pregnancy and lactation. Children <3 yr.
Lactation: secreted into breast milk, do not use if breastfeeding
Pregnancy-Lactation
Pregnancy Category: safety not established; weigh risk/benefit
Lactation: secreted into breast milk, do not use if breastfeeding
Interactions
Reduced platelet count with oral antidiabetics.
Potentially Fatal: May potentiate CNS effects of sedatives, hypnotics, antihistamines and alcohol.
Side Effects
Side effects of Ketotifen :
1-10%
Weight gain (5.3%), Rash (4%), Respiratory infection (4%), Abdominal pain (1.3%), Increased appetite (1.3%), Epistaxis (1.3%), Puffy eyelid (1.3%), Sleep disturbance (1.3%)
Mode of Action
Ketotifen selectively and noncompetitively inhibits the release of mediators from cells involved in hypersensitivity reactions. It is also a mast cell stabiliser.
Note
Orotifen 1mg Tablet generic name is Ketotifen. Orotifen 1mg Tablet is manufactured by General Pharmaceuticals Ltd.Orotifen is availble in all over Bangladesh.
Mes BD drug index information on Orotifen Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.