Optadex E/E Drops

Chloramphenicol 0.5% + Dexamethasone 0.1% Eye/Ear drop

500 mg + 100 mg/100 ml

Reman Drug Laboratories Ltd.

Pack size	5ml drop
Unite Price	70.26 BDT

Indications

Optadex E/E Drops is used for: Allergic conjunctivitis, Acute purulent conjunctivitis, Corneal ulceration, Keratitis disciformis, Post-herpetic keratitis, Allergic blepharitis, Acute and chronic iritis, Iridocyclitis, Otitis externa, infective and inflammatory ear infections.

Adult Dose

Ocular infections Adult: Instill 1 drop of asolution every 2 hr. Increase dosage interval upon improvement. To continue treatment for at least 48 hr after complete healing. Otic/Aural Otitis externa Adult: Instill 2-3 drops into the ear bid-tid.

Child Dose

Renal Dose

Administration

Contra Indications

History of hypersensitivity or toxic reaction to the drug; Perforated ear drum. Herpes simplex and other viral conditions of the eye or ear, mycosis.

Precautions

Avoid prolonged use. Discontinue immediately if local hypersensitivity reactions occur.

Pregnancy-Lactation

Interactions

Decreased effects of iron and vitamin B12 in anaemic patients. Phenobarbitone and rifampin reduce efficacy of chloramphenicol. Impairs the action of oral contraceptives.

Side Effects

Side effects of Chloramphenicol 0.5% + Dexamethasone 0.1% Eye/Ear drop : Ophthalmic application: Hypersensitivity reactions including rashes, fever and angioedema. Ear drops: Ototoxicity.

Mode of Action

Dexamethasone is a synthetic glucocorticoid which decreases inflammation by inhibiting the migration of leukocytes and reversal of increased capillary permeability. It suppresses normal immune response. Chloramphenicol inhibits bacterial protein synthesis by binding to 50s subunit of the bacterial ribosome, thus preventing peptide bond formation by peptidyl transferase.

Note

Optadex 500 mg + 100 mg/100 ml E/E Drops generic name is Chloramphenicol 0.5% + Dexamethasone 0.1% Eye/Ear drop. Optadex 500 mg + 100 mg/100 ml E/E Drops is manufactured by Reman Drug Laboratories Ltd.Optadex is availble in all over Bangladesh. Mes BD drug index information on Optadex E/E Drops is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Chloramphenicol 0.5% + Dexamethasone 0.1% Eye/Ear drop :

E/E Drops

Chlormet ^{5 mg + 1 mg/ml}

Beximco Pharmaceuticals Ltd.

E/E Drops

Cloradex ^0.1%+0.5%

Navana Pharmaceuticals Ltd.

E/E Drops

Cloram D ^{500 mg + 100 mg/100 ml}

Ibn Sina Pharmaceutical Ind. Ltd.

E/E Drops

Dexacol ^{500 mg + 100 mg/100 ml}

Opso Saline Ltd.

E/E Drops

Dexchlor ^{500 mg + 100 mg/100 ml}

G. A. Company Ltd.