Olestar Suspension
Cholestyramine
4 g
Everest Pharmaceuticals Ltd.
| Pack size | 10 Sachet in box |
|---|---|
| Unite Price | 130.00/Sachet BDT |
Indications
Olestar Suspension is used for:
Bile acid-induced diarrhoea; Hyperlipidaemias, Pruritus associated w/ partial biliary obstruction or primary biliary cirrhosis
Adult Dose
Hyperlipidaemias
Adult: 12-24 g daily in single dose or up to 4 divided doses.
Bile acid-induced diarrhoea
Adult: 12-24 g daily in single dose or up to 4 divided doses.
Pruritus associated with partial biliary obstruction or primary biliary cirrhosis
Adult: 4-8 g daily.
Child Dose
Hyperlipidaemias
Child: >6 yr: 240 mg/kg daily in divided doses.
Bile acid-induced diarrhoea
Child: >6 yr: 240 mg/kg daily in divided doses.
Pruritus associated with partial biliary obstruction or primary biliary cirrhosis
Child: >6 yr: 240 mg/kg daily in divided doses.
Renal Dose
Administration
May be taken with or without food. Do not take in the dry form. Mix w/ 150 mL of water or fruit juice, stir to a uniform consistency before taking.
Reconstitution: Mix the powder w/ 60-180 mL of water or another noncarbonated beverage (e.g. fruit juice) and stir to a uniform consistency. Alternatively, it may also be mixed w/ skimmed milk, thin soup or a pulpy fruit w/ high moisture content (e.g. applesauce or crushed pineapple).
Contra Indications
Complete biliary obstruction; hypersensitivity.
Precautions
Admin as a suspension in water or a flavored vehicle to minimise risk of oesophageal obstruction. May interfere with absorption of fat-soluble vitamins and folic acid and prolonged use may be associated with an increased bleeding tendency. Pregnancy; lactation.
Lactation: Drug does not enter breast milk; use with caution because of potential vitamin loss in mother
Pregnancy-Lactation
Pregnancy category: C
Lactation: Drug does not enter breast milk; use with caution because of potential vitamin loss in mother
Interactions
Delayed or reduced absorption of folic acid, thiazide diuretics, propranolol, digoxin and related glycosides, loperamide, phenylbutazone, barbiturates, oestrogens, progestogens, thyroid hormones, warfarin and other coumarin-derivative anticoagulants, iron salts, deferasirox and some antibacterials (e.g. tetracycline, penicillin G). May prevent absorption of fat-soluble vit. Slightly decreased rate of absorption of clofibrate. May interfere w/ absorption of oral phosphate supplements.
Side Effects
Side effects of Cholestyramine :
Constipation; faecal impaction; haemorrhoids; abdominal discomfort or pain; heartburn; flatulence; nausea; vomiting; diarrhoea; increased bleeding tendency (chronic use); osteoporosis; steatorrhoea (high doses); skin rashes; pruritus of the tongue, skin and perianal region; hyperchloraemic acidosis.
Mode of Action
Colestyramine binds with bile acids to form an insoluble complex which is excreted in the feces, resulting in increased loss of bile acid, thus increasing the oxidation of cholesterol to bile acids.
Note
Olestar 4 g Suspension generic name is Cholestyramine. Olestar 4 g Suspension is manufactured by Everest Pharmaceuticals Ltd.Olestar is availble in all over Bangladesh.
Mes BD drug index information on Olestar Suspension is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.