Noctin Tablet

Nitrazepam
5mg
Ambee Pharmaceuticals Ltd.
Pack size 100's pack
Unite Price 1.00 BDT

Indications

Noctin Tablet is used for: Insomnia

Adult Dose

Oral Short-term management of insomnia Adult: 5 mg at night; increase to 10 mg if necessary. Elderly: and debilitated patients: ?normal adult dose.

Child Dose

Oral Infantile spasms Child: Infants: 125 mcg/kg bid; gradually increase to 250-500 mcg/kg bid.

Renal Dose

Administration

May be taken with or without food.

Contra Indications

Myasthenia gravis, narrow-angle glaucoma, severe respiratory insufficiency, sleep apnoea syndrome, severe hepatic impairment, porphyria.

Precautions

May induce anterograde amnesia; caution patients to have uninterrupted sleep of 7-8 hr after ingestion of dose. May impair ability to drive or operate machinery. Depression, especially if suicidal risk may be present. History of drug abuse or acute alcoholism. Hepatic and renal impairment. Respiratory disease. Debilitated patients. Patients who are at risk of falls. Children, elderly. Pregnancy and lactation.

Pregnancy-Lactation

Interactions

CNS depressant effect increased with alcohol, barbiturates, TCAs, phenothiazines, morphine derivatives. Effects may be antagonised by theophylline. Increased levels/effects with probenecid. Reduced levels/effects with rifampicin. May reduce effects of levodopa.

Side Effects

Side effects of Nitrazepam : Hypotension, palpitation; agitation, aggressiveness, amnesia, ataxia, confusion, delusions, disorientation, dizziness, fatigue, hallucination, hangover, headache, irritability, nightmares, psychoses, rage, restlessness, sedation; rash; changes in libido; constipation, diarrhoea, excessive salivation, heartburn, nausea, vomiting; granulocytopenia, leukopenia; falling, muscle weakness; blurred or double vision; tinnitus (associated with withdrawal); aspiration, increased bronchial secretion, dyspnoea.

Mode of Action

Nitrazepam is a benzodiazepine with a pronounced sleep-inducing activity. It depresses the reticular-activating system in the brainstem by enhancing the inhibitory effect of GABA on brain cells, thus preventing excessive brain activity.

Note

Noctin 5mg Tablet generic name is Nitrazepam. Noctin 5mg Tablet is manufactured by Ambee Pharmaceuticals Ltd.Noctin is availble in all over Bangladesh. Mes BD drug index information on Noctin Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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