Nicoral Tablet

Nicorandil
10mg
General Pharmaceuticals Ltd.
Pack size 50's pack
Unite Price 6.00 BDT

Indications

Nicoral Tablet is used for: Angina pectoris

Adult Dose

Oral Angina pectoris Adult: 10 mg bid, increase if necessary. Usual dose: 10-20 mg bid. May use 5 mg bid for patients prone to headache. Max dose: 30 mg bid. Hepatic impairment: Dose reduction may be necessary.

Child Dose

Renal Dose

Administration

May be taken with or without food.

Contra Indications

Cardiogenic shock; hypotension; left ventricular failure with low filling pressure; lactation.

Precautions

Hypovolaemia, low systolic BP, acute pulmonary oedema, pregnancy. May impair ability to drive or operate machinery.

Pregnancy-Lactation

Interactions

Hypotensive interaction may occur with alcohol, TCAs, antihypertensives and other vasodilators. Potentially Fatal: Enhanced hypotensive effect with sildenafil and other phosphodiesterase type-5 inhibitors.

Side Effects

Side effects of Nicorandil : Headache (usually transitory), flushing, dizziness, nausea, vomiting and weakness. Hypotension and reflex tachycardia at high doses.

Mode of Action

Nicorandil dilates arterioles and large coronary arteries by opening the potassium channels, and stimulates guanylate cyclase causing venous vasodilatation. It therefore reduces preload and afterload, and improves coronary blood flow.

Note

Nicoral 10mg Tablet generic name is Nicorandil. Nicoral 10mg Tablet is manufactured by General Pharmaceuticals Ltd.Nicoral is availble in all over Bangladesh. Mes BD drug index information on Nicoral Tablet is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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