Indications
Naftifun Cream is used for:
Skin fungal infections, treatment of interdigital tinea pedis, tinea cruris, and tinea corporis
Adult Dose
Topical/Cutaneous
Skin fungal infections
Adult: As hydrochloride: Apply sufficient amount of cream once daily or gel bid, morning and evening.
Treatment duration: Tinea cruris and tinea corporis: 2-4 wk; tinea pedis: 4-6 wk; severe infections: May require prolonged treatment.
Child Dose
Renal Dose
Administration
Apply a thin layer to the affected areas plus half inch margin of healthy surrounding skin
Contra Indications
Hypersensitivity.
Precautions
Avoid contact with eyes, nose, mouth and other mucous membranes. Avoid use of occlusive dressings or wrappings. Discontinue use if irritation occurs. Pregnancy and lactation.
Pregnancy-Lactation
Pregnancy: There are no available data in pregnant women to inform the drug-associated risk for major birth defects and miscarriage; in animal reproduction studies, no adverse effects on embryofetal development were seen at oral doses administered during period of organogenesis up to 18 times maximum recommended human dose (MRHD) in pregnant rats or subcutaneous doses administered during period of organogenesis up to 2 times the MRHD in pregnant rats or 4 times the MRHD in pregnant rabbits
Lactation: There is no information available on presence of drug in human milk, effects of drug on breastfed infant, or effects of drug on milk production; lack of clinical data during lactation precludes clear determination of risk of drug to infant during lactation; consider development and health benefits of breastfeeding along with mother’s clinical need for drug and any potential adverse effects on breastfed infant from drug or from underlying maternal condition
Interactions
Side Effects
Side effects of Naftifine Topical :
Burning, stinging, dryness, redness, pruritus, local irritation, rash, skin tenderness.
Mode of Action
Naftifine is a synthetic allylamine antifungal that selectively inhibits the enzyme squalene monooxygenase resulting in reduced synthesis of the primary sterol, ergosterol, within the fungal membrane. It appears to have both fungicidal and fungistatic activity.
Note
Naftifun 2 gm/100 gm Cream generic name is Naftifine Topical. Naftifun 2 gm/100 gm Cream is manufactured by Kumudini Pharma Ltd.Naftifun is availble in all over Bangladesh.
Mes BD drug index information on Naftifun Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.