Muderm Ointment
Mupirocin 2% Topical
100 mg/5 gm
Globe Pharmaceuticals Ltd.
| Pack size | |
|---|---|
| Unite Price | 140.00 BDT |
Indications
Muderm Ointment is used for:
Impetigo, Folliculitis, Secondary skin infections
Adult Dose
Topical/Cutaneous
Impetigo
Adult: As 2% oint: Apply to affected area tid for 5-10 days; re-evaluate after 3-5 days if no clinical response.
Secondary skin infections
Adult: As 2% cream: Apply to affected area tid for up to 10 days; re-evaluate after 3-5 days if no clinical response.
Child Dose
Topical/Cutaneous
Impetigo
Child: >2 mth Apply to affected area tid for 5-10 days; re-evaluate after 3-5 days if no clinical response.
Secondary skin infections
Child: >3 mth Apply to affected area tid for up to 10 days; re-evaluate after 3-5 days if no clinical response.
Renal Dose
Administration
Contra Indications
This drug is contraindicated in individuals with a history of sensitivity reactions to Mupirocin or any of the components of the preparation.
Precautions
Patient w/ extensive burns and wounds. Renal impairment. Childn. Pregnancy and lactation. Prolonged use may result in overgrowth of nonsusceptible organisms, including fungi
Lactation: Not known if distributed into milk; recommended that nursing be temporarily discontinued during therapy
Pregnancy-Lactation
Pregnancy
There are insufficient human data to establish whether there is drug-associated risk with therapy in pregnant women; systemic absorption of mupirocin through intact human skin is minimal following topical administration of mupirocin ointment; no developmental toxicity was observed in rats or rabbits treated with mupirocin subcutaneously during organogenesis at doses of 160 or 40 mg per kg per day, respectively (22 and 11 times the human topical dose based on calculations of dose divided by the entire body surface area)
Lactation
Not known whether mupirocin is present in human milk, has effects on breastfed child, or has effects on milk production; however, breastfeeding is not expected to result in exposure of child to drug due to minimal systemic absorption following topical administration; developmental and health benefits of breastfeeding should be considered along with mother’s clinical need for therapy and any potential adverse effects on breastfed child from therapy or from underlying maternal condition
To minimize oral exposure of drug to children, a breast and/or nipple being treated with mupirocin ointment should be thoroughly washed prior to breastfeeding
Interactions
Side Effects
Side effects of Mupirocin 2% Topical :
Burning, stinging, pruritus, pain, rash, erythema, dry skin, tenderness, cellulitis, pain or bleeding secondary to eczema, secondary wound infection, urticaria, swelling, increased exudates, contact dermatitis, furunculosis, exfoliative dermatitis.
Rarely, systemic reactions (e.g. nausea, headache, dizziness, abdominal pain, ulcerative stomatitis, systemic allergic reactions).
Mode of Action
Mupirocin inhibits protein synthesis of the bacteria by binding to isoleucyl transfer RNA-synthetase. It is active against gram-positive and some gram-negative bacteria.
Note
Muderm 100 mg/5 gm Ointment generic name is Mupirocin 2% Topical. Muderm 100 mg/5 gm Ointment is manufactured by Globe Pharmaceuticals Ltd.Muderm is availble in all over Bangladesh.
Mes BD drug index information on Muderm Ointment is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.