Indications
Minoxil Solution is used for:
Male pattern baldness, Alopecia androgenetica
Adult Dose
Androgenetic Alopecia
Male: Apply 1 mL of 2% or 5% solution to affected areas of scalp BID; no more than 2 ml in 24 hours
Female: Apply 1 mL of 2% solution to affected areas of scalp BID
It should be used twice daily for four months or more before evidence of hair growth can be expected.
Child Dose
<18 years old: Safety & efficacy not established
Renal Dose
Administration
Hair and scalp should be thoroughly dry prior to topical application of Minoxidil. A dose of 1 ml Minoxidil cutaneous solution should be applied to the total affected areas of the scalp twice daily. The total dosage should not exceed 2 ml. If fingertips are used to facilitate drug application, hands should be washed afterwards.
Contra Indications
Minoxidil topical solution is contraindicated in patients with a history of hypersensitivity to Minoxidil or any of the other ingredients in the formulation such as propylene glycol or ethanol.
Precautions
Before using Minoxidil, the user should determine that the scalp is normal and healthy. Patients with known cardiovascular disease or cardiac arrhythmia should contact a physician before using Minoxidil. Minoxidil contains alcohol, which will cause burning and irritation of the eye. In the event of accidental contact with sensitive surfaces (eye, abraded skin and mucous membranes) the area should be bathed with large amount of cool tap water.
Lactation: following topical application of the drug is not known, but the drug has been shown to distribute into milk following oral administration in lactating women
Pregnancy-Lactation
Pregnancy Category: C
Lactation: Following topical application of the drug is not known, but the drug has been shown to distribute into milk following oral administration in lactating women
Interactions
Topical: Absorption may be increased with corticosteroids, retinoids, occlusive ointment bases.
Potentially Fatal: Severe orthostatic hypotension may occur with guanethidine.
Side Effects
Side effects of Minoxidil Topical :
1-10%
Allergic contact dermatitis (7.4%), Tendonitis (2.6%)
Frequency Not Defined
Irritation, Burning, Erythema at site of application, May see systemic effects (hypotension)
Mode of Action
Minoxidil is an antihypertensive with direct vasodilating property. It reduces elevated BP accompanied by reflex tachycardia, increased cardiac output and elevated plasma renin. Applied topically, minoxidil stimulates hair growth secondary to vasodilation, increases cutaneous blood flow and stimulates resting hair follicles.
Note
Minoxil 5% Solution generic name is Minoxidil Topical. Minoxil 5% Solution is manufactured by Opsonin Pharma LimitedMinoxil is availble in all over Bangladesh.
Mes BD drug index information on Minoxil Solution is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.