Melafresh Cream
Fluocinolone 0.01% + Hydroquinone 4% + Tretinoin 0.05% Topical
0.01%+4%+0.05%
Cosmic Pharma Ltd.
| Pack size | |
|---|---|
| Unite Price | 190.00 BDT |
Indications
Melafresh Cream is used for:
Melasma
Adult Dose
Topical/Cutaneous
Moderate to severe melasma of the face
Adult: Apply a thin layer onto the hyperpigmented areas of melasma once daily, 30 minutes before bedtime. Treatment duration should not exceed 8 wk.
Child Dose
Renal Dose
Administration
Wash face gently before application; rinse & pat dry
Apply thin film to hyperpigmented area & 1/2 inch surrounding skin
Do not use occlusive dressing
Contra Indications
A history of hypersensitivity, allergy, or intolerance to this product or any of its components.
Precautions
Cream contains hydroquinone and tretinoin that may cause mild to moderate irritation such as skin reddening, peeling, mild burning sensation, dryness, and pruritus. Transient skin reddening or mild burning sensation does not preclude treatment. If a reaction suggests hypersensitivity or chemical irritation, the use of the medication should be discontinued.
Cream also contains the corticosteroid fluocinolone acetonide. Systemic absorption of topical corticosteroids can produce reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency after withdrawal of treatment. Manifestations of Cushing’s syndrome, hyperglycemia, and glucosuria can also be produced by systemic absorption of topical corticosteroid while on treatment. If HPA axis suppression is noted, Cream should be discontinued.
Lactation: not known whether excreted in breast milk; use caution
Pregnancy-Lactation
Pregnancy Category: C
Lactation: not known whether excreted in breast milk; use caution
Interactions
Medicated or abrasive soaps & cleansers, soaps & cosmetics w/ drying effects, products w/ high conc of alcohol & astringent, & other irritants or keratolytic drugs. Medications w/ photosensitizing effects.
Side Effects
Side effects of Fluocinolone 0.01% + Hydroquinone 4% + Tretinoin 0.05% Topical :
>10%
Erythema (41-45%), Desquamation (36-40%), Burning (16-20%), Dryness (11-15%), Pruritis (11-15%)
1-10%
Acne (5%)
Mode of Action
Fluocinolone acetonide is a synthetic fluorinated corticosteroid that is used topically for its anti-inflammatory, anti-pruritic and vasoconstrictive properties. Hydroquinone is used as a depigmenting agent. Tretinoin is a retinoid that is appears to stimulate mitosis, increases turnover of follicular epithelial cells and reduces their cohesiveness.
Note
Melafresh 0.01%+4%+0.05% Cream generic name is Fluocinolone 0.01% + Hydroquinone 4% + Tretinoin 0.05% Topical. Melafresh 0.01%+4%+0.05% Cream is manufactured by Cosmic Pharma Ltd.Melafresh is availble in all over Bangladesh.
Mes BD drug index information on Melafresh Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.